Safar J - Search Results

1

Dominant-negative inhibition of prion replication in transgenic mice.

Perrier V, Kaneko K, Safar J, Vergara J, Tremblay P, DeArmond SJ, Cohen FE, Prusiner SB, Wallace AC. Perrier V, et al. Among authors: safar j. Proc Natl Acad Sci U S A. 2002 Oct 1;99(20):13079-84. doi: 10.1073/pnas.182425299. Epub 2002 Sep 23. Proc Natl Acad Sci U S A. 2002. PMID: 12271119 Free PMC article.

2

Identification of a prion protein epitope modulating transmission of bovine spongiform encephalopathy prions to transgenic mice.

Scott MR, Safar J, Telling G, Nguyen O, Groth D, Torchia M, Koehler R, Tremblay P, Walther D, Cohen FE, DeArmond SJ, Prusiner SB. Scott MR, et al. Among authors: safar j. Proc Natl Acad Sci U S A. 1997 Dec 23;94(26):14279-84. doi: 10.1073/pnas.94.26.14279. Proc Natl Acad Sci U S A. 1997. PMID: 9405603 Free PMC article.

3

Prion protein selectively binds copper(II) ions.

Stöckel J, Safar J, Wallace AC, Cohen FE, Prusiner SB. Stöckel J, et al. Among authors: safar j. Biochemistry. 1998 May 19;37(20):7185-93. doi: 10.1021/bi972827k. Biochemistry. 1998. PMID: 9585530

4

Eight prion strains have PrP(Sc) molecules with different conformations.

Safar J, Wille H, Itri V, Groth D, Serban H, Torchia M, Cohen FE, Prusiner SB. Safar J, et al. Nat Med. 1998 Oct;4(10):1157-65. doi: 10.1038/2654. Nat Med. 1998. PMID: 9771749

5

Molecular studies of prion diseases.

Safar J, Prusiner SB. Safar J, et al. Prog Brain Res. 1998;117:421-34. doi: 10.1016/s0079-6123(08)64030-3. Prog Brain Res. 1998. PMID: 9932423 Review. No abstract available.

6

Prion protein of 106 residues creates an artifical transmission barrier for prion replication in transgenic mice.

Supattapone S, Bosque P, Muramoto T, Wille H, Aagaard C, Peretz D, Nguyen HO, Heinrich C, Torchia M, Safar J, Cohen FE, DeArmond SJ, Prusiner SB, Scott M. Supattapone S, et al. Among authors: safar j. Cell. 1999 Mar 19;96(6):869-78. doi: 10.1016/s0092-8674(00)80596-6. Cell. 1999. PMID: 10102274 Free article.

7

A synthetic peptide initiates Gerstmann-Sträussler-Scheinker (GSS) disease in transgenic mice.

Kaneko K, Ball HL, Wille H, Zhang H, Groth D, Torchia M, Tremblay P, Safar J, Prusiner SB, DeArmond SJ, Baldwin MA, Cohen FE. Kaneko K, et al. Among authors: safar j. J Mol Biol. 2000 Jan 28;295(4):997-1007. doi: 10.1006/jmbi.1999.3386. J Mol Biol. 2000. PMID: 10656806

8

Mimicking dominant negative inhibition of prion replication through structure-based drug design.

Perrier V, Wallace AC, Kaneko K, Safar J, Prusiner SB, Cohen FE. Perrier V, et al. Among authors: safar j. Proc Natl Acad Sci U S A. 2000 May 23;97(11):6073-8. doi: 10.1073/pnas.97.11.6073. Proc Natl Acad Sci U S A. 2000. PMID: 10823951 Free PMC article.

9

Quantitative traits of prion strains are enciphered in the conformation of the prion protein.

Safar J, Cohen FE, Prusiner SB. Safar J, et al. Arch Virol Suppl. 2000;(16):227-35. doi: 10.1007/978-3-7091-6308-5_22. Arch Virol Suppl. 2000. PMID: 11214926

10

Branched polyamines cure prion-infected neuroblastoma cells.

Supattapone S, Wille H, Uyechi L, Safar J, Tremblay P, Szoka FC, Cohen FE, Prusiner SB, Scott MR. Supattapone S, et al. Among authors: safar j. J Virol. 2001 Apr;75(7):3453-61. doi: 10.1128/JVI.75.7.3453-3461.2001. J Virol. 2001. PMID: 11238871 Free PMC article.

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