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Lysophosphatidylcholines prime the NADPH oxidase and stimulate multiple neutrophil functions through changes in cytosolic calcium.
Silliman CC, Elzi DJ, Ambruso DR, Musters RJ, Hamiel C, Harbeck RJ, Paterson AJ, Bjornsen AJ, Wyman TH, Kelher M, England KM, McLaughlin-Malaxecheberria N, Barnett CC, Aiboshi J, Bannerjee A. Silliman CC, et al. Among authors: kelher m. J Leukoc Biol. 2003 Apr;73(4):511-24. doi: 10.1189/jlb.0402179. J Leukoc Biol. 2003. PMID: 12660226
Soluble CD40 ligand accumulates in stored blood components, primes neutrophils through CD40, and is a potential cofactor in the development of transfusion-related acute lung injury.
Khan SY, Kelher MR, Heal JM, Blumberg N, Boshkov LK, Phipps R, Gettings KF, McLaughlin NJ, Silliman CC. Khan SY, et al. Among authors: kelher mr. Blood. 2006 Oct 1;108(7):2455-62. doi: 10.1182/blood-2006-04-017251. Epub 2006 Jun 13. Blood. 2006. PMID: 16772606 Free PMC article.
70 results