Pestell RG - Search Results

1

Caveolin-1-deficient mice show accelerated mammary gland development during pregnancy, premature lactation, and hyperactivation of the Jak-2/STAT5a signaling cascade.

Park DS, Lee H, Frank PG, Razani B, Nguyen AV, Parlow AF, Russell RG, Hulit J, Pestell RG, Lisanti MP. Park DS, et al. Among authors: pestell rg. Mol Biol Cell. 2002 Oct;13(10):3416-30. doi: 10.1091/mbc.02-05-0071. Mol Biol Cell. 2002. PMID: 12388746 Free PMC article.

2

Loss of caveolin-1 gene expression accelerates the development of dysplastic mammary lesions in tumor-prone transgenic mice.

Williams TM, Cheung MW, Park DS, Razani B, Cohen AW, Muller WJ, Di Vizio D, Chopra NG, Pestell RG, Lisanti MP. Williams TM, et al. Among authors: pestell rg. Mol Biol Cell. 2003 Mar;14(3):1027-42. doi: 10.1091/mbc.e02-08-0503. Mol Biol Cell. 2003. PMID: 12631721 Free PMC article.

3

Combined loss of INK4a and caveolin-1 synergistically enhances cell proliferation and oncogene-induced tumorigenesis: role of INK4a/CAV-1 in mammary epithelial cell hyperplasia.

Williams TM, Lee H, Cheung MW, Cohen AW, Razani B, Iyengar P, Scherer PE, Pestell RG, Lisanti MP. Williams TM, et al. Among authors: pestell rg. J Biol Chem. 2004 Jun 4;279(23):24745-56. doi: 10.1074/jbc.M402064200. Epub 2004 Mar 25. J Biol Chem. 2004. PMID: 15044451 Free article.

4

Caveolin-1-deficient mice have an increased mammary stem cell population with upregulation of Wnt/beta-catenin signaling.

Sotgia F, Williams TM, Cohen AW, Minetti C, Pestell RG, Lisanti MP. Sotgia F, et al. Among authors: pestell rg. Cell Cycle. 2005 Dec;4(12):1808-16. doi: 10.4161/cc.4.12.2198. Epub 2005 Dec 22. Cell Cycle. 2005. PMID: 16294019

5

Genetic ablation of caveolin-1 in mammary epithelial cells increases milk production and hyper-activates STAT5a signaling.

Sotgia F, Schubert W, Pestell RG, Lisanti MP. Sotgia F, et al. Among authors: pestell rg. Cancer Biol Ther. 2006 Mar;5(3):292-7. doi: 10.4161/cbt.5.3.2390. Epub 2006 Mar 9. Cancer Biol Ther. 2006. PMID: 16418573 Free article.

6

Caveolin-1 mutations (P132L and null) and the pathogenesis of breast cancer: caveolin-1 (P132L) behaves in a dominant-negative manner and caveolin-1 (-/-) null mice show mammary epithelial cell hyperplasia.

Lee H, Park DS, Razani B, Russell RG, Pestell RG, Lisanti MP. Lee H, et al. Among authors: pestell rg. Am J Pathol. 2002 Oct;161(4):1357-69. doi: 10.1016/S0002-9440(10)64412-4. Am J Pathol. 2002. PMID: 12368209 Free PMC article.

7

p42/44 MAP kinase-dependent and -independent signaling pathways regulate caveolin-1 gene expression. Activation of Ras-MAP kinase and protein kinase a signaling cascades transcriptionally down-regulates caveolin-1 promoter activity.

Engelman JA, Zhang XL, Razani B, Pestell RG, Lisanti MP. Engelman JA, et al. Among authors: pestell rg. J Biol Chem. 1999 Nov 5;274(45):32333-41. doi: 10.1074/jbc.274.45.32333. J Biol Chem. 1999. PMID: 10542274 Free article.

8

Evidence that Myc isoforms transcriptionally repress caveolin-1 gene expression via an INR-dependent mechanism.

Park DS, Razani B, Lasorella A, Schreiber-Agus N, Pestell RG, Iavarone A, Lisanti MP. Park DS, et al. Among authors: pestell rg. Biochemistry. 2001 Mar 20;40(11):3354-62. doi: 10.1021/bi002787b. Biochemistry. 2001. PMID: 11258956

9

Caveolin-1 expression negatively regulates cell cycle progression by inducing G(0)/G(1) arrest via a p53/p21(WAF1/Cip1)-dependent mechanism.

Galbiati F, Volonté D, Liu J, Capozza F, Frank PG, Zhu L, Pestell RG, Lisanti MP. Galbiati F, et al. Among authors: pestell rg. Mol Biol Cell. 2001 Aug;12(8):2229-44. doi: 10.1091/mbc.12.8.2229. Mol Biol Cell. 2001. PMID: 11514613 Free PMC article.

10

Ligand-independent activation of oestrogen receptor alpha by caveolin-1.

Schlegel A, Wang C, Pestell RG, Lisanti MP. Schlegel A, et al. Among authors: pestell rg. Biochem J. 2001 Oct 1;359(Pt 1):203-10. doi: 10.1042/0264-6021:3590203. Biochem J. 2001. PMID: 11563984 Free PMC article.

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