Baillie TA - Search Results

1

Extrapolation of diclofenac clearance from in vitro microsomal metabolism data: role of acyl glucuronidation and sequential oxidative metabolism of the acyl glucuronide.

Kumar S, Samuel K, Subramanian R, Braun MP, Stearns RA, Chiu SH, Evans DC, Baillie TA. Kumar S, et al. Among authors: baillie ta. J Pharmacol Exp Ther. 2002 Dec;303(3):969-78. doi: 10.1124/jpet.102.038992. J Pharmacol Exp Ther. 2002. PMID: 12438516

2

Roles of human hepatic cytochrome P450s 2C9 and 3A4 in the metabolic activation of diclofenac.

Tang W, Stearns RA, Wang RW, Chiu SH, Baillie TA. Tang W, et al. Among authors: baillie ta. Chem Res Toxicol. 1999 Feb;12(2):192-9. doi: 10.1021/tx9802217. Chem Res Toxicol. 1999. PMID: 10027798

3

Studies on cytochrome P-450-mediated bioactivation of diclofenac in rats and in human hepatocytes: identification of glutathione conjugated metabolites.

Tang W, Stearns RA, Bandiera SM, Zhang Y, Raab C, Braun MP, Dean DC, Pang J, Leung KH, Doss GA, Strauss JR, Kwei GY, Rushmore TH, Chiu SH, Baillie TA. Tang W, et al. Among authors: baillie ta. Drug Metab Dispos. 1999 Mar;27(3):365-72. Drug Metab Dispos. 1999. PMID: 10064567

4

Role of a potent inhibitory monoclonal antibody to cytochrome P-450 3A4 in assessment of human drug metabolism.

Mei Q, Tang C, Assang C, Lin Y, Slaughter D, Rodrigues AD, Baillie TA, Rushmore TH, Shou M. Mei Q, et al. Among authors: baillie ta. J Pharmacol Exp Ther. 1999 Nov;291(2):749-59. J Pharmacol Exp Ther. 1999. PMID: 10525096

5

Interaction of diclofenac and quinidine in monkeys: stimulation of diclofenac metabolism.

Tang W, Stearns RA, Kwei GY, Iliff SA, Miller RR, Egan MA, Yu NX, Dean DC, Kumar S, Shou M, Lin JH, Baillie TA. Tang W, et al. Among authors: baillie ta. J Pharmacol Exp Ther. 1999 Dec;291(3):1068-74. J Pharmacol Exp Ther. 1999. PMID: 10565826

6

Cytochrome P450 3A4-mediated interaction of diclofenac and quinidine.

Ngui JS, Tang W, Stearns RA, Shou M, Miller RR, Zhang Y, Lin JH, Baillie TA. Ngui JS, et al. Among authors: baillie ta. Drug Metab Dispos. 2000 Sep;28(9):1043-50. Drug Metab Dispos. 2000. PMID: 10950847

7

In vitro stimulation of warfarin metabolism by quinidine: increases in the formation of 4'- and 10-hydroxywarfarin.

Ngui JS, Chen Q, Shou M, Wang RW, Stearns RA, Baillie TA, Tang W. Ngui JS, et al. Among authors: baillie ta. Drug Metab Dispos. 2001 Jun;29(6):877-86. Drug Metab Dispos. 2001. PMID: 11353757

8

Bioactivation of diclofenac via benzoquinone imine intermediates-identification of urinary mercapturic acid derivatives in rats and humans.

Poon GK, Chen Q, Teffera Y, Ngui JS, Griffin PR, Braun MP, Doss GA, Freeden C, Stearns RA, Evans DC, Baillie TA, Tang W. Poon GK, et al. Among authors: baillie ta. Drug Metab Dispos. 2001 Dec;29(12):1608-13. Drug Metab Dispos. 2001. PMID: 11717180

9

Mechanistic studies on the reversible metabolism of rofecoxib to 5-hydroxyrofecoxib in the rat: evidence for transient ring opening of a substituted 2-furanone derivative using stable isotope-labeling techniques.

Baillie TA, Halpin RA, Matuszewski BK, Geer LA, Chavez-Eng CM, Dean D, Braun M, Doss G, Jones A, Marks T, Melillo D, Vyas KP. Baillie TA, et al. Drug Metab Dispos. 2001 Dec;29(12):1614-28. Drug Metab Dispos. 2001. PMID: 11717181

10

Cytochrome P450 3A4-mediated oxidative conversion of a cyano to an amide group in the metabolism of pinacidil.

Zhang Z, Li Y, Stearns RA, Ortiz De Montellano PR, Baillie TA, Tang W. Zhang Z, et al. Among authors: baillie ta. Biochemistry. 2002 Feb 26;41(8):2712-8. doi: 10.1021/bi0119971. Biochemistry. 2002. PMID: 11851418

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