Sakamoto S - Search Results

1

YM872: a selective, potent and highly water-soluble alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor antagonist.

Takahashi M, Kohara A, Shishikura J, Kawasaki-Yatsugi S, Ni JW, Yatsugi S, Sakamoto S, Okada M, Shimizu-Sasamata M, Yamaguchi T. Takahashi M, et al. Among authors: sakamoto s. CNS Drug Rev. 2002 Winter;8(4):337-52. doi: 10.1111/j.1527-3458.2002.tb00232.x. CNS Drug Rev. 2002. PMID: 12481190 Free PMC article. Review.

2

Functional characterization of YM928, a novel moncompetitive alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor antagonist.

Ohno K, Tsutsumi R, Matsumoto N, Yamashita H, Amada Y, Shishikura J, Yatsugi HI, Okada M, Sakamoto S, Yamaguchi T. Ohno K, et al. Among authors: sakamoto s. J Pharmacol Exp Ther. 2003 Jul;306(1):66-72. doi: 10.1124/jpet.103.049973. Epub 2003 Mar 26. J Pharmacol Exp Ther. 2003. PMID: 12660313

3

YM90K: pharmacological characterization as a selective and potent alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate/kainate receptor antagonist.

Shimizu-Sasamata M, Kawasaki-Yatsugi S, Okada M, Sakamoto S, Yatsugi S, Togami J, Hatanaka K, Ohmori J, Koshiya K, Usuda S, Murase K. Shimizu-Sasamata M, et al. Among authors: sakamoto s. J Pharmacol Exp Ther. 1996 Jan;276(1):84-92. J Pharmacol Exp Ther. 1996. PMID: 8558460

4

Novel alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate receptor antagonists: synthesis and structure-activity relationships of 6-(1H-imidazol-1-yl)-7-nitro-2,3(1H,4H)-pyrido[2,3-b]pyrazinedione and related compounds.

Ohmori J, Kubota H, Shimizu-Sasamata M, Okada M, Sakamoto S. Ohmori J, et al. Among authors: sakamoto s. J Med Chem. 1996 Mar 15;39(6):1331-8. doi: 10.1021/jm950304+. J Med Chem. 1996. PMID: 8632440

5

Neuroprotective effect of YM90K, a novel AMPA/kainate receptor antagonist, in focal cerebral ischemia in cats.

Yatsugi S, Takahashi M, Kawasaki-Yatsugi S, Koshiya K, Sakamoto S, Uematsu D, Shimizu-Sasamata M. Yatsugi S, et al. Among authors: sakamoto s. J Cereb Blood Flow Metab. 1996 Sep;16(5):959-66. doi: 10.1097/00004647-199609000-00020. J Cereb Blood Flow Metab. 1996. PMID: 8784240

6

YM872, a novel selective alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor antagonist, reduces brain damage after permanent focal cerebral ischemia in cats.

Takahashi M, Ni JW, Kawasaki-Yatsugi S, Toya T, Yatsugi SI, Shimizu-Sasamata M, Koshiya K, Shishikura JI, Sakamoto S, Yamaguchi T. Takahashi M, et al. Among authors: sakamoto s. J Pharmacol Exp Ther. 1998 Feb;284(2):467-73. J Pharmacol Exp Ther. 1998. PMID: 9454786

7

In-vitro characterization of YM872, a selective, potent and highly water-soluble alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate receptor antagonist.

Kohara A, Okada M, Tsutsumi R, Ohno K, Takahashi M, Shimizu-Sasamata M, Shishikura J, Inami H, Sakamoto S, Yamaguchi T. Kohara A, et al. Among authors: sakamoto s. J Pharm Pharmacol. 1998 Jul;50(7):795-801. doi: 10.1111/j.2042-7158.1998.tb07142.x. J Pharm Pharmacol. 1998. PMID: 9720630

8

Novel AMPA receptor antagonists: synthesis and structure-activity relationships of 1-hydroxy-7-(1H-imidazol-1-yl)-6-nitro-2,3(1H,4H)- quinoxalinedione and related compounds.

Ohmori J, Shimizu-Sasamata M, Okada M, Sakamoto S. Ohmori J, et al. Among authors: sakamoto s. J Med Chem. 1996 Sep 27;39(20):3971-9. doi: 10.1021/jm960387+. J Med Chem. 1996. PMID: 8831762

9

Effects of 2-[N-(4-chlorophenyl)-N-methylamino]-4H-pyrido[3.2-e]-1,3-thiazin-4-one (YM928), an orally active alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor antagonist, in models of generalized epileptic seizure in mice and rats.

Yamashita H, Ohno K, Amada Y, Hattori H, Ozawa-Funatsu Y, Toya T, Inami H, Shishikura J, Sakamoto S, Okada M, Yamaguchi T. Yamashita H, et al. Among authors: sakamoto s. J Pharmacol Exp Ther. 2004 Jan;308(1):127-33. doi: 10.1124/jpet.103.058495. Epub 2003 Oct 20. J Pharmacol Exp Ther. 2004. PMID: 14569061

10

Suppression of fully kindled seizure and retardation of kindling acquisition by YM928 in the rat kindling model of epilepsy.

Yamashita H, Ohno K, Inami H, Shishikura J, Sakamoto S, Okada M, Yamaguchi T. Yamashita H, et al. Among authors: sakamoto s. Eur J Pharmacol. 2004 Jun 28;494(2-3):147-54. doi: 10.1016/j.ejphar.2004.04.052. Eur J Pharmacol. 2004. PMID: 15212968

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