Bryant SD - Search Results

1

Endomorphins and related opioid peptides.

Okada Y, Tsuda Y, Bryant SD, Lazarus LH. Okada Y, et al. Among authors: bryant sd. Vitam Horm. 2002;65:257-79. doi: 10.1016/s0083-6729(02)65067-8. Vitam Horm. 2002. PMID: 12481550 Review.

2

Structural studies of [2',6'-dimethyl-L-tyrosine1]endomorphin-2 analogues: enhanced activity and cis orientation of the Dmt-Pro amide bond.

Okada Y, Fujita Y, Motoyama T, Tsuda Y, Yokoi T, Li T, Sasaki Y, Ambo A, Jinsmaa Y, Bryant SD, Lazarus LH. Okada Y, et al. Among authors: bryant sd. Bioorg Med Chem. 2003 May 1;11(9):1983-94. doi: 10.1016/s0968-0896(03)00068-3. Bioorg Med Chem. 2003. PMID: 12670649

3

Unique high-affinity synthetic mu-opioid receptor agonists with central- and systemic-mediated analgesia.

Okada Y, Tsuda Y, Fujita Y, Yokoi T, Sasaki Y, Ambo A, Konishi R, Nagata M, Salvadori S, Jinsmaa Y, Bryant SD, Lazarus LH. Okada Y, et al. Among authors: bryant sd. J Med Chem. 2003 Jul 17;46(15):3201-9. doi: 10.1021/jm020459z. J Med Chem. 2003. PMID: 12852751

4

Development of potent bifunctional endomorphin-2 analogues with mixed mu-/delta-opioid agonist and delta-opioid antagonist properties.

Fujita Y, Tsuda Y, Li T, Motoyama T, Takahashi M, Shimizu Y, Yokoi T, Sasaki Y, Ambo A, Kita A, Jinsmaa Y, Bryant SD, Lazarus LH, Okada Y. Fujita Y, et al. Among authors: bryant sd. J Med Chem. 2004 Jul 1;47(14):3591-9. doi: 10.1021/jm030649p. J Med Chem. 2004. PMID: 15214786

5

Development of potent mu-opioid receptor ligands using unique tyrosine analogues of endomorphin-2.

Li T, Fujita Y, Tsuda Y, Miyazaki A, Ambo A, Sasaki Y, Jinsmaa Y, Bryant SD, Lazarus LH, Okada Y. Li T, et al. Among authors: bryant sd. J Med Chem. 2005 Jan 27;48(2):586-92. doi: 10.1021/jm049384k. J Med Chem. 2005. PMID: 15658871

6

Studies on the structure-activity relationship of 2',6'-dimethyl-l-tyrosine (Dmt) derivatives: bioactivity profile of H-Dmt-NH-CH(3).

Fujita Y, Tsuda Y, Motoyama T, Li T, Miyazaki A, Yokoi T, Sasaki Y, Ambo A, Niizuma H, Jinsmaa Y, Bryant SD, Lazarus LH, Okada Y. Fujita Y, et al. Among authors: bryant sd. Bioorg Med Chem Lett. 2005 Feb 1;15(3):599-602. doi: 10.1016/j.bmcl.2004.11.040. Bioorg Med Chem Lett. 2005. PMID: 15664820

7

New series of potent delta-opioid antagonists containing the H-Dmt-Tic-NH-hexyl-NH-R motif.

Li T, Shiotani K, Miyazaki A, Fujita Y, Tsuda Y, Ambo A, Sasaki Y, Jinsmaa Y, Marczak E, Bryant SD, Lazarus LH, Okada Y. Li T, et al. Among authors: bryant sd. Bioorg Med Chem Lett. 2005 Dec 15;15(24):5517-20. doi: 10.1016/j.bmcl.2005.08.073. Epub 2005 Sep 23. Bioorg Med Chem Lett. 2005. PMID: 16183273

8

Potent Dmt-Tic pharmacophoric delta- and mu-opioid receptor antagonists.

Li T, Fujita Y, Shiotani K, Miyazaki A, Tsuda Y, Ambo A, Sasaki Y, Jinsmaa Y, Marczak E, Bryant SD, Salvadori S, Lazarus LH, Okada Y. Li T, et al. Among authors: bryant sd. J Med Chem. 2005 Dec 15;48(25):8035-44. doi: 10.1021/jm050377l. J Med Chem. 2005. PMID: 16335927

9

Synthesis of 3,6-bis[H-Tyr/H-Dmt-NH(CH2)m,n]-2(1H)pyrazinone derivatives: function of alkyl chain length on opioid activity.

Shiotani K, Li T, Miyazaki A, Tsuda Y, Bryant SD, Ambo A, Sasaki Y, Lazarus LH, Okada Y. Shiotani K, et al. Among authors: bryant sd. Bioorg Med Chem Lett. 2006 Nov 15;16(22):5793-6. doi: 10.1016/j.bmcl.2006.08.079. Epub 2006 Sep 1. Bioorg Med Chem Lett. 2006. PMID: 16949282 Free PMC article.

10

Transformation of mu-opioid receptor agonists into biologically potent mu-opioid receptor antagonists.

Li T, Jinsmaa Y, Nedachi M, Miyazaki A, Tsuda Y, Ambo A, Sasaki Y, Bryant SD, Marczak E, Li Q, Swartzwelder HS, Lazarus LH, Okada Y. Li T, et al. Among authors: bryant sd. Bioorg Med Chem. 2007 Feb 1;15(3):1237-51. doi: 10.1016/j.bmc.2006.11.019. Epub 2006 Nov 14. Bioorg Med Chem. 2007. PMID: 17142049

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