Groll M - Search Results

1

The core structure of TMC-95A is a promising lead for reversible proteasome inhibition.

Kaiser M, Groll M, Renner C, Huber R, Moroder L. Kaiser M, et al. Among authors: groll m. Angew Chem Int Ed Engl. 2002 Mar 1;41(5):780-3. doi: 10.1002/1521-3773(20020301)41:5<780::aid-anie780>3.0.co;2-v. Angew Chem Int Ed Engl. 2002. PMID: 12491334 No abstract available.

2

Substrate access and processing by the 20S proteasome core particle.

Groll M, Huber R. Groll M, et al. Int J Biochem Cell Biol. 2003 May;35(5):606-16. doi: 10.1016/s1357-2725(02)00390-4. Int J Biochem Cell Biol. 2003. PMID: 12672453 Review.

3

Synthesis of a TMC-95A ketomethylene analogue by cyclization via intramolecular Suzuki coupling.

Kaiser M, Siciliano C, Assfalg-Machleidt I, Groll M, Milbradt AG, Moroder L. Kaiser M, et al. Among authors: groll m. Org Lett. 2003 Sep 18;5(19):3435-7. doi: 10.1021/ol035178f. Org Lett. 2003. PMID: 12967293

4

Binding mode of TMC-95A analogues to eukaryotic 20S proteasome.

Kaiser M, Groll M, Siciliano C, Assfalg-Machleidt I, Weyher E, Kohno J, Milbradt AG, Renner C, Huber R, Moroder L. Kaiser M, et al. Among authors: groll m. Chembiochem. 2004 Sep 6;5(9):1256-66. doi: 10.1002/cbic.200400096. Chembiochem. 2004. PMID: 15368577

5

TMC-95A analogues with endocyclic biphenyl ether group as proteasome inhibitors.

Kaiser M, Milbradt AG, Siciliano C, Assfalg-Machleidt I, Machleidt W, Groll M, Renner C, Moroder L. Kaiser M, et al. Among authors: groll m. Chem Biodivers. 2004 Jan;1(1):161-73. doi: 10.1002/cbdv.200490008. Chem Biodivers. 2004. PMID: 17191784

6

Elucidation of the α-keto-aldehyde binding mechanism: a lead structure motif for proteasome inhibition.

Gräwert MA, Gallastegui N, Stein M, Schmidt B, Kloetzel PM, Huber R, Groll M. Gräwert MA, et al. Among authors: groll m. Angew Chem Int Ed Engl. 2011 Jan 10;50(2):542-4. doi: 10.1002/anie.201005488. Angew Chem Int Ed Engl. 2011. PMID: 21154547 No abstract available.

7

Bivalency as a principle for proteasome inhibition.

Loidl G, Groll M, Musiol HJ, Huber R, Moroder L. Loidl G, et al. Among authors: groll m. Proc Natl Acad Sci U S A. 1999 May 11;96(10):5418-22. doi: 10.1073/pnas.96.10.5418. Proc Natl Acad Sci U S A. 1999. PMID: 10318898 Free PMC article.

8

Probing structural determinants distal to the site of hydrolysis that control substrate specificity of the 20S proteasome.

Groll M, Nazif T, Huber R, Bogyo M. Groll M, et al. Chem Biol. 2002 May;9(5):655-62. doi: 10.1016/s1074-5521(02)00144-8. Chem Biol. 2002. PMID: 12031672

9

Investigations on the maturation and regulation of archaebacterial proteasomes.

Groll M, Brandstetter H, Bartunik H, Bourenkow G, Huber R. Groll M, et al. J Mol Biol. 2003 Mar 14;327(1):75-83. doi: 10.1016/s0022-2836(03)00080-9. J Mol Biol. 2003. PMID: 12614609

10

Inhibitors of the eukaryotic 20S proteasome core particle: a structural approach.

Groll M, Huber R. Groll M, et al. Biochim Biophys Acta. 2004 Nov 29;1695(1-3):33-44. doi: 10.1016/j.bbamcr.2004.09.025. Biochim Biophys Acta. 2004. PMID: 15571807 Free article. Review.

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