Anderson J - Search Results

1

3-[(2-Methyl-1,3-thiazol-4-yl)ethynyl]-pyridine: a potent and highly selective metabotropic glutamate subtype 5 receptor antagonist with anxiolytic activity.

Cosford ND, Tehrani L, Roppe J, Schweiger E, Smith ND, Anderson J, Bristow L, Brodkin J, Jiang X, McDonald I, Rao S, Washburn M, Varney MA. Cosford ND, et al. Among authors: anderson j. J Med Chem. 2003 Jan 16;46(2):204-6. doi: 10.1021/jm025570j. J Med Chem. 2003. PMID: 12519057

2

Cyclohexenyl- and dehydropiperidinyl-alkynyl pyridines as potent metabotropic glutamate subtype 5 (mGlu5) receptor antagonists.

Chua PC, Nagasawa JY, Bleicher LS, Munoz B, Schweiger EJ, Tehrani L, Anderson JJ, Cramer M, Chung J, Green MD, King CD, Reyes-Manalo G, Cosford ND. Chua PC, et al. Among authors: anderson jj. Bioorg Med Chem Lett. 2005 Oct 15;15(20):4589-93. doi: 10.1016/j.bmcl.2005.06.099. Bioorg Med Chem Lett. 2005. PMID: 16115767

3

Role of metabotropic glutamate receptor subtype 5 (mGluR5) in the maintenance of cold hypersensitivity following a peripheral mononeuropathy in the rat.

Urban MO, Hama AT, Bradbury M, Anderson J, Varney MA, Bristow L. Urban MO, et al. Among authors: anderson j. Neuropharmacology. 2003 Jun;44(8):983-93. doi: 10.1016/s0028-3908(03)00118-7. Neuropharmacology. 2003. PMID: 12763091

4

Effects of ketamine and N-methyl-D-aspartate on glutamate and dopamine release in the rat prefrontal cortex: modulation by a group II selective metabotropic glutamate receptor agonist LY379268.

Lorrain DS, Baccei CS, Bristow LJ, Anderson JJ, Varney MA. Lorrain DS, et al. Among authors: anderson jj. Neuroscience. 2003;117(3):697-706. doi: 10.1016/s0306-4522(02)00652-8. Neuroscience. 2003. PMID: 12617973

5

Metabotropic glutamate receptor 5 antagonist-induced stimulation of hypothalamic-pituitary-adrenal axis activity: interaction with serotonergic systems.

Bradbury MJ, Giracello DR, Chapman DF, Holtz G, Schaffhauser H, Rao SP, Varney MA, Anderson JJ. Bradbury MJ, et al. Among authors: anderson jj. Neuropharmacology. 2003 Apr;44(5):562-72. doi: 10.1016/s0028-3908(03)00048-0. Neuropharmacology. 2003. PMID: 12668042

6

Discovery of novel heteroarylazoles that are metabotropic glutamate subtype 5 receptor antagonists with anxiolytic activity.

Roppe J, Smith ND, Huang D, Tehrani L, Wang B, Anderson J, Brodkin J, Chung J, Jiang X, King C, Munoz B, Varney MA, Prasit P, Cosford ND. Roppe J, et al. Among authors: anderson j. J Med Chem. 2004 Sep 9;47(19):4645-8. doi: 10.1021/jm049828c. J Med Chem. 2004. PMID: 15341479

7

[3H]Methoxymethyl-3-[(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridine binding to metabotropic glutamate receptor subtype 5 in rodent brain: in vitro and in vivo characterization.

Anderson JJ, Rao SP, Rowe B, Giracello DR, Holtz G, Chapman DF, Tehrani L, Bradbury MJ, Cosford ND, Varney MA. Anderson JJ, et al. J Pharmacol Exp Ther. 2002 Dec;303(3):1044-51. doi: 10.1124/jpet.102.040618. J Pharmacol Exp Ther. 2002. PMID: 12438526

8

In vivo receptor occupancy of mGlu5 receptor antagonists using the novel radioligand [3H]3-methoxy-5-(pyridin-2-ylethynyl)pyridine).

Anderson JJ, Bradbury MJ, Giracello DR, Chapman DF, Holtz G, Roppe J, King C, Cosford ND, Varney MA. Anderson JJ, et al. Eur J Pharmacol. 2003 Jul 18;473(1):35-40. doi: 10.1016/s0014-2999(03)01935-6. Eur J Pharmacol. 2003. PMID: 12877935

9

Discovery of novel modulators of metabotropic glutamate receptor subtype-5.

Wang B, Vernier JM, Rao S, Chung J, Anderson JJ, Brodkin JD, Jiang X, Gardner MF, Yang X, Munoz B. Wang B, et al. Among authors: anderson jj. Bioorg Med Chem. 2004 Jan 2;12(1):17-21. doi: 10.1016/j.bmc.2003.10.021. Bioorg Med Chem. 2004. PMID: 14697765

10

5-[(2-Methyl-1,3-thiazol-4-yl)ethynyl]-2,3'-bipyridine: a highly potent, orally active metabotropic glutamate subtype 5 (mGlu5) receptor antagonist with anxiolytic activity.

Roppe JR, Wang B, Huang D, Tehrani L, Kamenecka T, Schweiger EJ, Anderson JJ, Brodkin J, Jiang X, Cramer M, Chung J, Reyes-Manalo G, Munoz B, Cosford ND. Roppe JR, et al. Among authors: anderson jj. Bioorg Med Chem Lett. 2004 Aug 2;14(15):3993-6. doi: 10.1016/j.bmcl.2004.05.037. Bioorg Med Chem Lett. 2004. PMID: 15225713

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