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RGT, a synthetic peptide corresponding to the integrin beta 3 cytoplasmic C-terminal sequence, selectively inhibits outside-in signaling in human platelets by disrupting the interaction of integrin alpha IIb beta 3 with Src kinase.
Su X, Mi J, Yan J, Flevaris P, Lu Y, Liu H, Ruan Z, Wang X, Kieffer N, Chen S, Du X, Xi X. Su X, et al. Among authors: xi x. Blood. 2008 Aug 1;112(3):592-602. doi: 10.1182/blood-2007-09-110437. Epub 2008 Apr 8. Blood. 2008. PMID: 18398066 Free PMC article.
2,131 results