Adelman K - Search Results

1

Interaction of T4 AsiA with its target sites in the RNA polymerase sigma70 subunit leads to distinct and opposite effects on transcription.

Minakhin L, Niedziela-Majka A, Kuznedelov K, Adelman K, Urbauer JL, Heyduk T, Severinov K. Minakhin L, et al. Among authors: adelman k. J Mol Biol. 2003 Feb 21;326(3):679-90. doi: 10.1016/s0022-2836(02)01442-0. J Mol Biol. 2003. PMID: 12581632

2

TP63 fusions drive multicomplex enhancer rewiring, lymphomagenesis, and EZH2 dependence.

Wu G, Yoshida N, Liu J, Zhang X, Xiong Y, Heavican-Foral TB, Mandato E, Liu H, Nelson GM, Yang L, Chen R, Donovan KA, Jones MK, Roshal M, Zhang Y, Xu R, Nirmal AJ, Jain S, Leahy C, Jones KL, Stevenson KE, Galasso N, Ganesan N, Chang T, Wu WC, Louissaint A, Debaize L, Yoon H, Dal Cin P, Chan WC, Ho Sui SJ, Ng SY, Feldman AL, Horwitz SM, Adelman K, Fischer ES, Chen CW, Weinstock DM, Brown M. Wu G, et al. Among authors: adelman k. Sci Transl Med. 2023 Sep 20;15(714):eadi7244. doi: 10.1126/scitranslmed.adi7244. Epub 2023 Sep 20. Sci Transl Med. 2023. PMID: 37729434 Free PMC article.

3

Splicing modulators impair DNA damage response and induce killing of cohesin-mutant MDS and AML.

Wheeler EC, Martin BJE, Doyle WC, Neaher S, Conway CA, Pitton CN, Gorelov RA, Donahue M, Jann JC, Abdel-Wahab O, Taylor J, Seiler M, Buonamici S, Pikman Y, Garcia JS, Belizaire R, Adelman K, Tothova Z. Wheeler EC, et al. Among authors: adelman k. Sci Transl Med. 2024 Jan 3;16(728):eade2774. doi: 10.1126/scitranslmed.ade2774. Epub 2024 Jan 3. Sci Transl Med. 2024. PMID: 38170787 Free PMC article.

4

Oncogenic CDK13 mutations impede nuclear RNA surveillance.

Insco ML, Abraham BJ, Dubbury SJ, Kaltheuner IH, Dust S, Wu C, Chen KY, Liu D, Bellaousov S, Cox AM, Martin BJE, Zhang T, Ludwig CG, Fabo T, Modhurima R, Esgdaille DE, Henriques T, Brown KM, Chanock SJ, Geyer M, Adelman K, Sharp PA, Young RA, Boutz PL, Zon LI. Insco ML, et al. Among authors: adelman k. Science. 2023 Apr 21;380(6642):eabn7625. doi: 10.1126/science.abn7625. Epub 2023 Apr 21. Science. 2023. PMID: 37079685 Free PMC article.

5

RNA polymerase II pausing is essential during spermatogenesis for appropriate gene expression and completion of meiosis.

Kaye EG, Basavaraju K, Nelson GM, Zomer HD, Roy D, Joseph II, Rajabi-Toustani R, Qiao H, Adelman K, Reddi PP. Kaye EG, et al. Among authors: adelman k. Nat Commun. 2024 Jan 29;15(1):848. doi: 10.1038/s41467-024-45177-3. Nat Commun. 2024. PMID: 38287033 Free PMC article.

6

Integrator is a global promoter-proximal termination complex.

Wagner EJ, Tong L, Adelman K. Wagner EJ, et al. Among authors: adelman k. Mol Cell. 2023 Feb 2;83(3):416-427. doi: 10.1016/j.molcel.2022.11.012. Epub 2023 Jan 11. Mol Cell. 2023. PMID: 36634676 Free PMC article. Review.

7

Decoding the Epigenetics and Chromatin Loop Dynamics of Androgen Receptor-Mediated Transcription.

Lack N, Altintas UB, Seo JH, Giambartolomei C, Ozturan D, Fortunato B, Nelson G, Goldman S, Adelman K, Hach F, Freedman M. Lack N, et al. Among authors: adelman k. Res Sq [Preprint]. 2024 Feb 2:rs.3.rs-3854707. doi: 10.21203/rs.3.rs-3854707/v1. Res Sq. 2024. Update in: Nat Commun. 2024 Nov 3;15(1):9494. doi: 10.1038/s41467-024-53758-5 PMID: 38352568 Free PMC article. Updated. Preprint.

8

Bacteriophage T4 MotA and AsiA proteins suffice to direct Escherichia coli RNA polymerase to initiate transcription at T4 middle promoters.

Ouhammouch M, Adelman K, Harvey SR, Orsini G, Brody EN. Ouhammouch M, et al. Among authors: adelman k. Proc Natl Acad Sci U S A. 1995 Feb 28;92(5):1451-5. doi: 10.1073/pnas.92.5.1451. Proc Natl Acad Sci U S A. 1995. PMID: 7877999 Free PMC article.

9

Main-chain NMR assignments for AsiA.

Urbauer JL, Adelman K, Brody EN. Urbauer JL, et al. Among authors: adelman k. J Biomol NMR. 1997 Sep;10(2):205-6. doi: 10.1023/a:1018343223888. J Biomol NMR. 1997. PMID: 9369017 No abstract available.

10

Conserved regions 4.1 and 4.2 of sigma(70) constitute the recognition sites for the anti-sigma factor AsiA, and AsiA is a dimer free in solution.

Urbauer JL, Adelman K, Urbauer RJ, Simeonov MF, Gilmore JM, Zolkiewski M, Brody EN. Urbauer JL, et al. Among authors: adelman k. J Biol Chem. 2001 Nov 2;276(44):41128-32. doi: 10.1074/jbc.M106400200. Epub 2001 Aug 22. J Biol Chem. 2001. PMID: 11518715 Free article.

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