Wyllie FS - Search Results

1

Telomere-based proliferative lifespan barriers in Werner-syndrome fibroblasts involve both p53-dependent and p53-independent mechanisms.

Davis T, Singhrao SK, Wyllie FS, Haughton MF, Smith PJ, Wiltshire M, Wynford-Thomas D, Jones CJ, Faragher RG, Kipling D. Davis T, et al. Among authors: wyllie fs. J Cell Sci. 2003 Apr 1;116(Pt 7):1349-57. doi: 10.1242/jcs.00331. J Cell Sci. 2003. PMID: 12615976 Free article.

2

An analysis of replicative senescence in dermal fibroblasts derived from chronic leg wounds predicts that telomerase therapy would fail to reverse their disease-specific cellular and proteolytic phenotype.

Stephens P, Cook H, Hilton J, Jones CJ, Haughton MF, Wyllie FS, Skinner JW, Harding KG, Kipling D, Thomas DW. Stephens P, et al. Among authors: wyllie fs. Exp Cell Res. 2003 Feb 1;283(1):22-35. doi: 10.1016/s0014-4827(02)00021-6. Exp Cell Res. 2003. PMID: 12565817

3

A P53-dependent, telomere-independent proliferative life span barrier in human astrocytes consistent with the molecular genetics of glioma development.

Evans RJ, Wyllie FS, Wynford-Thomas D, Kipling D, Jones CJ. Evans RJ, et al. Among authors: wyllie fs. Cancer Res. 2003 Aug 15;63(16):4854-61. Cancer Res. 2003. PMID: 12941806

4

The role of cellular senescence in Werner syndrome: toward therapeutic intervention in human premature aging.

Davis T, Wyllie FS, Rokicki MJ, Bagley MC, Kipling D. Davis T, et al. Among authors: wyllie fs. Ann N Y Acad Sci. 2007 Apr;1100:455-69. doi: 10.1196/annals.1395.051. Ann N Y Acad Sci. 2007. PMID: 17460211 Review.

5

Evaluating the role of p38 MAP kinase in growth of Werner syndrome fibroblasts.

Davis T, Bachler MA, Wyllie FS, Bagley MC, Kipling D. Davis T, et al. Among authors: wyllie fs. Ann N Y Acad Sci. 2010 Jun;1197:45-8. doi: 10.1111/j.1749-6632.2010.05195.x. Ann N Y Acad Sci. 2010. PMID: 20536832 Review.

6

Mutant p53 can delay growth arrest and loss of CDK2 activity in senescing human fibroblasts without reducing p21(WAF1) expression.

Wyllie F, Haughton M, Bartek J, Rowson J, Wynford-Thomas D. Wyllie F, et al. Exp Cell Res. 2003 May 1;285(2):236-42. doi: 10.1016/s0014-4827(03)00050-8. Exp Cell Res. 2003. PMID: 12706118

7

S phase cell-cycle arrest following DNA damage is independent of the p53/p21(WAF1) signalling pathway.

Wyllie FS, Haughton MF, Bond JA, Rowson JM, Jones CJ, Wynford-Thomas D. Wyllie FS, et al. Oncogene. 1996 Mar 7;12(5):1077-82. Oncogene. 1996. PMID: 8649799

8

The tumour suppressor gene p53 as a regulator of proliferative life-span and tumour progression.

Wynford-Thomas D, Jones CJ, Wyllie FS. Wynford-Thomas D, et al. Among authors: wyllie fs. Biol Signals. 1996 May-Jun;5(3):139-53. doi: 10.1159/000109184. Biol Signals. 1996. PMID: 8864059 Review.

9

Dissociation of telomere dynamics from telomerase activity in human thyroid cancer cells.

Jones CJ, Soley A, Skinner JW, Gupta J, Haughton MF, Wyllie FS, Schlumberger M, Bacchetti S, Wynford-Thomas D. Jones CJ, et al. Among authors: wyllie fs. Exp Cell Res. 1998 May 1;240(2):333-9. doi: 10.1006/excr.1998.3944. Exp Cell Res. 1998. PMID: 9597006

10

Control of replicative life span in human cells: barriers to clonal expansion intermediate between M1 senescence and M2 crisis.

Bond JA, Haughton MF, Rowson JM, Smith PJ, Gire V, Wynford-Thomas D, Wyllie FS. Bond JA, et al. Among authors: wyllie fs. Mol Cell Biol. 1999 Apr;19(4):3103-14. doi: 10.1128/MCB.19.4.3103. Mol Cell Biol. 1999. PMID: 10082577 Free PMC article.

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