Riggins JN - Search Results

1

Endogenous generation of reactive oxidants and electrophiles and their reactions with DNA and protein.

Marnett LJ, Riggins JN, West JD. Marnett LJ, et al. Among authors: riggins jn. J Clin Invest. 2003 Mar;111(5):583-93. doi: 10.1172/JCI18022. J Clin Invest. 2003. PMID: 12618510 Free PMC article. Review. No abstract available.

2

Exocyclic DNA lesions stimulate DNA cleavage mediated by human topoisomerase II alpha in vitro and in cultured cells.

Vélez-Cruz R, Riggins JN, Daniels JS, Cai H, Guengerich FP, Marnett LJ, Osheroff N. Vélez-Cruz R, et al. Among authors: riggins jn. Biochemistry. 2005 Mar 15;44(10):3972-81. doi: 10.1021/bi0478289. Biochemistry. 2005. PMID: 15751973

3

Differential DNA recognition and cleavage by EcoRI dependent on the dynamic equilibrium between the two forms of the malondialdehyde-deoxyguanosine adduct.

VanderVeen LA, Druckova A, Riggins JN, Sorrells JL, Guengerich FP, Marnett LJ. VanderVeen LA, et al. Among authors: riggins jn. Biochemistry. 2005 Apr 5;44(13):5024-33. doi: 10.1021/bi0472898. Biochemistry. 2005. PMID: 15794640

4

Kinetic and thermodynamic analysis of the hydrolytic ring-opening of the malondialdehyde-deoxyguanosine adduct, 3-(2'-deoxy-beta-D-erythro-pentofuranosyl)- pyrimido[1,2-alpha]purin-10(3H)-one.

Riggins JN, Daniels JS, Rouzer CA, Marnett LJ. Riggins JN, et al. J Am Chem Soc. 2004 Jul 7;126(26):8237-43. doi: 10.1021/ja040009r. J Am Chem Soc. 2004. PMID: 15225065

5

Kinetics and mechanism of the general-acid-catalyzed ring-closure of the malondialdehyde-DNA adduct, N2-(3-oxo-1-propenyl)deoxyguanosine (N2OPdG-), to 3-(2'-Deoxy-beta-D-erythro-pentofuranosyl)pyrimido[1,2-alpha]purin- 10(3H)-one (M1dG).

Riggins JN, Pratt DA, Voehler M, Daniels JS, Marnett LJ. Riggins JN, et al. J Am Chem Soc. 2004 Sep 1;126(34):10571-81. doi: 10.1021/ja040010q. J Am Chem Soc. 2004. PMID: 15327313

6

In vitro bypass of malondialdehyde-deoxyguanosine adducts: differential base selection during extension by the Klenow fragment of DNA polymerase I is the critical determinant of replication outcome.

Hashim MF, Riggins JN, Schnetz-Boutaud N, Voehler M, Stone MP, Marnett LJ. Hashim MF, et al. Among authors: riggins jn. Biochemistry. 2004 Sep 21;43(37):11828-35. doi: 10.1021/bi049360f. Biochemistry. 2004. PMID: 15362868

7

Reactivity and mutagenicity of endogenous DNA oxopropenylating agents: base propenals, malondialdehyde, and N(epsilon)-oxopropenyllysine.

Plastaras JP, Riggins JN, Otteneder M, Marnett LJ. Plastaras JP, et al. Among authors: riggins jn. Chem Res Toxicol. 2000 Dec;13(12):1235-42. doi: 10.1021/tx0001631. Chem Res Toxicol. 2000. PMID: 11123964

8

Mutagenicity of the malondialdehyde oligomerization products 2-(3'-oxo-1'-propenyl)-malondialdehyde and 2,4-dihydroxymethylene-3-(2,2-dimethoxyethyl)glutaraldehyde in Salmonella.

Riggins JN, Marnett LJ. Riggins JN, et al. Mutat Res. 2001 Oct 18;497(1-2):153-7. doi: 10.1016/s1383-5718(01)00253-4. Mutat Res. 2001. PMID: 11525918

9

Malondialdehyde adducts in DNA arrest transcription by T7 RNA polymerase and mammalian RNA polymerase II.

Cline SD, Riggins JN, Tornaletti S, Marnett LJ, Hanawalt PC. Cline SD, et al. Among authors: riggins jn. Proc Natl Acad Sci U S A. 2004 May 11;101(19):7275-80. doi: 10.1073/pnas.0402252101. Epub 2004 Apr 27. Proc Natl Acad Sci U S A. 2004. PMID: 15123825 Free PMC article.

10

Covalent adduction of human serum albumin by 4-hydroxy-2-nonenal: kinetic analysis of competing alkylation reactions.

Szapacs ME, Riggins JN, Zimmerman LJ, Liebler DC. Szapacs ME, et al. Among authors: riggins jn. Biochemistry. 2006 Sep 5;45(35):10521-8. doi: 10.1021/bi060535q. Biochemistry. 2006. PMID: 16939204

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