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A neurodevelopmental disorder mutation locks G proteins in the transitory pre-activated state.
Knight KM, Krumm BE, Kapolka NJ, Ludlam WG, Cui M, Mani S, Prytkova I, Obarow EG, Lefevre TJ, Wei W, Ma N, Huang XP, Fay JF, Vaidehi N, Smrcka AV, Slesinger PA, Logothetis DE, Martemyanov KA, Roth BL, Dohlman HG. Knight KM, et al. Nat Commun. 2024 Aug 5;15(1):6643. doi: 10.1038/s41467-024-50964-z. Nat Commun. 2024. PMID: 39103320 Free PMC article.
Molecular annotation of G protein variants in a neurological disorder.
Knight KM, Obarow EG, Wei W, Mani S, Esteller MI, Cui M, Ma N, Martin SA, Brinson E, Hewitt N, Soden GM, Logothetis DE, Vaidehi N, Dohlman HG. Knight KM, et al. Cell Rep. 2023 Dec 26;42(12):113578. doi: 10.1016/j.celrep.2023.113578. Epub 2023 Dec 2. Cell Rep. 2023. PMID: 38043061 Free PMC article. No abstract available.
Molecular annotation of G protein variants in a neurological disorder.
Knight KM, Obarow EG, Wei W, Mani S, Esteller MI, Cui M, Ma N, Martin SA, Brinson E, Hewitt N, Soden GM, Logothetis DE, Vaidehi N, Dohlman HG. Knight KM, et al. Cell Rep. 2023 Dec 26;42(12):113462. doi: 10.1016/j.celrep.2023.113462. Epub 2023 Nov 18. Cell Rep. 2023. PMID: 37980565 Free PMC article.
Subcellular Imaging of Neuronal Calcium Handling In Vivo.
Doser R, Knight KM, Deihl E, Hoerndli F. Doser R, et al. Among authors: knight km. J Vis Exp. 2023 Mar 17;(193):10.3791/64928. doi: 10.3791/64928. J Vis Exp. 2023. PMID: 37010315 Free PMC article.
Catalytic site mutations confer multiple states of G protein activation.
Hewitt N, Ma N, Arang N, Martin SA, Prakash A, DiBerto JF, Knight KM, Ghosh S, Olsen RHJ, Roth BL, Gutkind JS, Vaidehi N, Campbell SL, Dohlman HG. Hewitt N, et al. Among authors: knight km. Sci Signal. 2023 Feb 14;16(772):eabq7842. doi: 10.1126/scisignal.abq7842. Epub 2023 Feb 14. Sci Signal. 2023. PMID: 36787384 Free PMC article.
44 results