Farris W - Search Results

1

Insulin-degrading enzyme regulates the levels of insulin, amyloid beta-protein, and the beta-amyloid precursor protein intracellular domain in vivo.

Farris W, Mansourian S, Chang Y, Lindsley L, Eckman EA, Frosch MP, Eckman CB, Tanzi RE, Selkoe DJ, Guenette S. Farris W, et al. Proc Natl Acad Sci U S A. 2003 Apr 1;100(7):4162-7. doi: 10.1073/pnas.0230450100. Epub 2003 Mar 12. Proc Natl Acad Sci U S A. 2003. PMID: 12634421 Free PMC article.

2

Enhanced proteolysis of beta-amyloid in APP transgenic mice prevents plaque formation, secondary pathology, and premature death.

Leissring MA, Farris W, Chang AY, Walsh DM, Wu X, Sun X, Frosch MP, Selkoe DJ. Leissring MA, et al. Among authors: farris w. Neuron. 2003 Dec 18;40(6):1087-93. doi: 10.1016/s0896-6273(03)00787-6. Neuron. 2003. PMID: 14687544 Free article.

3

Partial loss-of-function mutations in insulin-degrading enzyme that induce diabetes also impair degradation of amyloid beta-protein.

Farris W, Mansourian S, Leissring MA, Eckman EA, Bertram L, Eckman CB, Tanzi RE, Selkoe DJ. Farris W, et al. Am J Pathol. 2004 Apr;164(4):1425-34. doi: 10.1016/s0002-9440(10)63229-4. Am J Pathol. 2004. PMID: 15039230 Free PMC article.

4

Alternative splicing of human insulin-degrading enzyme yields a novel isoform with a decreased ability to degrade insulin and amyloid beta-protein.

Farris W, Leissring MA, Hemming ML, Chang AY, Selkoe DJ. Farris W, et al. Biochemistry. 2005 May 3;44(17):6513-25. doi: 10.1021/bi0476578. Biochemistry. 2005. PMID: 15850385

5

Effects of prolonged angiotensin-converting enzyme inhibitor treatment on amyloid beta-protein metabolism in mouse models of Alzheimer disease.

Hemming ML, Selkoe DJ, Farris W. Hemming ML, et al. Among authors: farris w. Neurobiol Dis. 2007 Apr;26(1):273-81. doi: 10.1016/j.nbd.2007.01.004. Epub 2007 Jan 25. Neurobiol Dis. 2007. PMID: 17321748 Free PMC article.

6

Kinetics of amyloid beta-protein degradation determined by novel fluorescence- and fluorescence polarization-based assays.

Leissring MA, Lu A, Condron MM, Teplow DB, Stein RL, Farris W, Selkoe DJ. Leissring MA, et al. Among authors: farris w. J Biol Chem. 2003 Sep 26;278(39):37314-20. doi: 10.1074/jbc.M305627200. Epub 2003 Jul 16. J Biol Chem. 2003. PMID: 12867419 Free article.

7

Alternative translation initiation generates a novel isoform of insulin-degrading enzyme targeted to mitochondria.

Leissring MA, Farris W, Wu X, Christodoulou DC, Haigis MC, Guarente L, Selkoe DJ. Leissring MA, et al. Among authors: farris w. Biochem J. 2004 Nov 1;383(Pt. 3):439-46. doi: 10.1042/BJ20041081. Biochem J. 2004. PMID: 15285718 Free PMC article.

8

Decreased catalytic activity of the insulin-degrading enzyme in chromosome 10-linked Alzheimer disease families.

Kim M, Hersh LB, Leissring MA, Ingelsson M, Matsui T, Farris W, Lu A, Hyman BT, Selkoe DJ, Bertram L, Tanzi RE. Kim M, et al. Among authors: farris w. J Biol Chem. 2007 Mar 16;282(11):7825-32. doi: 10.1074/jbc.M609168200. Epub 2007 Jan 22. J Biol Chem. 2007. PMID: 17244626 Free article.

9

Loss of neprilysin function promotes amyloid plaque formation and causes cerebral amyloid angiopathy.

Farris W, Schütz SG, Cirrito JR, Shankar GM, Sun X, George A, Leissring MA, Walsh DM, Qiu WQ, Holtzman DM, Selkoe DJ. Farris W, et al. Am J Pathol. 2007 Jul;171(1):241-51. doi: 10.2353/ajpath.2007.070105. Am J Pathol. 2007. PMID: 17591969 Free PMC article.

10

Effects of chronic glucocorticoid administration on insulin-degrading enzyme and amyloid-beta peptide in the aged macaque.

Kulstad JJ, McMillan PJ, Leverenz JB, Cook DG, Green PS, Peskind ER, Wilkinson CW, Farris W, Mehta PD, Craft S. Kulstad JJ, et al. Among authors: farris w. J Neuropathol Exp Neurol. 2005 Feb;64(2):139-46. doi: 10.1093/jnen/64.2.139. J Neuropathol Exp Neurol. 2005. PMID: 15751228

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

29 results

Search Page

Filters