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Characterization of a bicyclic peptide neuropilin-1 (NP-1) antagonist (EG3287) reveals importance of vascular endothelial growth factor exon 8 for NP-1 binding and role of NP-1 in KDR signaling.
Jia H, Bagherzadeh A, Hartzoulakis B, Jarvis A, Löhr M, Shaikh S, Aqil R, Cheng L, Tickner M, Esposito D, Harris R, Driscoll PC, Selwood DL, Zachary IC. Jia H, et al. J Biol Chem. 2006 May 12;281(19):13493-13502. doi: 10.1074/jbc.M512121200. Epub 2006 Mar 2. J Biol Chem. 2006. PMID: 16513643 Free article.
Neuropilins: structure, function and role in disease.
Pellet-Many C, Frankel P, Jia H, Zachary I. Pellet-Many C, et al. Among authors: zachary i. Biochem J. 2008 Apr 15;411(2):211-26. doi: 10.1042/BJ20071639. Biochem J. 2008. PMID: 18363553 Review.
Anti-chemorepulsive effects of vascular endothelial growth factor and placental growth factor-2 in dorsal root ganglion neurons are mediated via neuropilin-1 and cyclooxygenase-derived prostanoid production.
Cheng L, Jia H, Löhr M, Bagherzadeh A, Holmes DI, Selwood D, Zachary I. Cheng L, et al. Among authors: zachary i. J Biol Chem. 2004 Jul 16;279(29):30654-61. doi: 10.1074/jbc.M402488200. Epub 2004 May 4. J Biol Chem. 2004. PMID: 15126502 Free article.
156 results