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Leads for development of new naphthalenesulfonate derivatives with enhanced antiangiogenic activity: crystal structure of acidic fibroblast growth factor in complex with 5-amino-2-naphthalene sulfonate.
Fernández-Tornero C, Lozano RM, Redondo-Horcajo M, Gómez AM, López JC, Quesada E, Uriel C, Valverde S, Cuevas P, Romero A, Giménez-Gallego G. Fernández-Tornero C, et al. Among authors: cuevas p. J Biol Chem. 2003 Jun 13;278(24):21774-81. doi: 10.1074/jbc.M212833200. Epub 2003 Apr 3. J Biol Chem. 2003. PMID: 12676958 Free article.
Gentisic acid, a compound associated with plant defense and a metabolite of aspirin, heads a new class of in vivo fibroblast growth factor inhibitors.
Fernández IS, Cuevas P, Angulo J, López-Navajas P, Canales-Mayordomo A, González-Corrochano R, Lozano RM, Valverde S, Jiménez-Barbero J, Romero A, Giménez-Gallego G. Fernández IS, et al. Among authors: cuevas p. J Biol Chem. 2010 Apr 9;285(15):11714-29. doi: 10.1074/jbc.M109.064618. Epub 2010 Feb 9. J Biol Chem. 2010. PMID: 20145243 Free PMC article.
Synthesis of the blood circulating C-terminal fragment of insulin-like growth factor (IGF)-binding protein-4 in its native conformation. Crystallization, heparin and IGF binding, and osteogenic activity.
Fernández-Tornero C, Lozano RM, Rivas G, Jiménez MA, Ständker L, Díaz-Gonzalez D, Forssmann WG, Cuevas P, Romero A, Giménez-Gallego G. Fernández-Tornero C, et al. Among authors: cuevas p. J Biol Chem. 2005 May 13;280(19):18899-907. doi: 10.1074/jbc.M500587200. Epub 2005 Feb 26. J Biol Chem. 2005. PMID: 15735305 Free article.
Dobesilate is an angiogenesis inhibitor.
Cuevas P, Sanchez I, Lozano RM, Gimenez-Gallego G. Cuevas P, et al. Eur J Med Res. 2005 Sep 12;10(9):369-72. Eur J Med Res. 2005. PMID: 16183547 Free article.
Fibroblast growth factor and cerebral ischaemia.
Cuevas P, Carceller F, Giménez-Gallego G. Cuevas P, et al. Neurol Res. 1994 Jun;16(3):181-3. doi: 10.1080/01616412.1994.11740222. Neurol Res. 1994. PMID: 7936085 Review.
250 results