MRP1 and glucosylceramide are coordinately over expressed and enriched in rafts during multidrug resistance acquisition in colon cancer cells.
Klappe K, Hinrichs JW, Kroesen BJ, Sietsma H, Kok JW.
Klappe K, et al.
Int J Cancer. 2004 Jul 1;110(4):511-22. doi: 10.1002/ijc.20140.
Int J Cancer. 2004.
PMID: 15122583
Previously we have described a novel multidrug-resistant cell line, HT29(col), which displayed over expression of the multidrug-resistance protein 1 (MRP1) and an altered sphingolipid composition, including enhanced levels of glucosylceramide (GlcCer; Kok JW, Veldman RJ, Klapp …
Previously we have described a novel multidrug-resistant cell line, HT29(col), which displayed over expression of the multidrug-resistance p …