Glabe CG - Search Results

1

Dityrosine cross-linked Abeta peptides: fibrillar beta-structure in Abeta(1-40) is conducive to formation of dityrosine cross-links but a dityrosine cross-link in Abeta(8-14) does not induce beta-structure.

Yoburn JC, Tian W, Brower JO, Nowick JS, Glabe CG, Van Vranken DL. Yoburn JC, et al. Among authors: glabe cg. Chem Res Toxicol. 2003 Apr;16(4):531-5. doi: 10.1021/tx025666g. Chem Res Toxicol. 2003. PMID: 12703970

2

Heterodivalent linked macrocyclic β-sheets with enhanced activity against Aβ aggregation: two sites are better than one.

Cheng PN, Spencer R, Woods RJ, Glabe CG, Nowick JS. Cheng PN, et al. Among authors: glabe cg. J Am Chem Soc. 2012 Aug 29;134(34):14179-84. doi: 10.1021/ja305416a. Epub 2012 Aug 17. J Am Chem Soc. 2012. PMID: 22827298 Free PMC article.

3

Out-of-register β-sheets suggest a pathway to toxic amyloid aggregates.

Liu C, Zhao M, Jiang L, Cheng PN, Park J, Sawaya MR, Pensalfini A, Gou D, Berk AJ, Glabe CG, Nowick J, Eisenberg D. Liu C, et al. Among authors: glabe cg. Proc Natl Acad Sci U S A. 2012 Dec 18;109(51):20913-8. doi: 10.1073/pnas.1218792109. Epub 2012 Dec 3. Proc Natl Acad Sci U S A. 2012. PMID: 23213214 Free PMC article.

4

Distinct early folding and aggregation properties of Alzheimer amyloid-beta peptides Abeta40 and Abeta42: stable trimer or tetramer formation by Abeta42.

Chen YR, Glabe CG. Chen YR, et al. Among authors: glabe cg. J Biol Chem. 2006 Aug 25;281(34):24414-22. doi: 10.1074/jbc.M602363200. Epub 2006 Jun 29. J Biol Chem. 2006. PMID: 16809342 Free article.

5

Complement activation by cross-linked truncated and chimeric full-length beta-amyloid.

Cribbs DH, Velazquez P, Soreghan B, Glabe CG, Tenner AJ. Cribbs DH, et al. Among authors: glabe cg. Neuroreport. 1997 Nov 10;8(16):3457-62. doi: 10.1097/00001756-199711100-00009. Neuroreport. 1997. PMID: 9427307

6

A conformation change in the carboxyl terminus of Alzheimer's Abeta (1-40) accompanies the transition from dimer to fibril as revealed by fluorescence quenching analysis.

Garzon-Rodriguez W, Vega A, Sepulveda-Becerra M, Milton S, Johnson DA, Yatsimirsky AK, Glabe CG. Garzon-Rodriguez W, et al. Among authors: glabe cg. J Biol Chem. 2000 Jul 28;275(30):22645-9. doi: 10.1074/jbc.M000756200. J Biol Chem. 2000. PMID: 10806193 Free article.

7

The influence of the carboxyl terminus of the Alzheimer Abeta peptide on its conformation, aggregation, and neurotoxic properties.

Soreghan B, Pike C, Kayed R, Tian W, Milton S, Cotman C, Glabe CG. Soreghan B, et al. Among authors: glabe cg. Neuromolecular Med. 2002;1(1):81-94. doi: 10.1385/NMM:1:1:81. Neuromolecular Med. 2002. PMID: 12025818

8

Structural differences between amyloid beta oligomers.

Breydo L, Kurouski D, Rasool S, Milton S, Wu JW, Uversky VN, Lednev IK, Glabe CG. Breydo L, et al. Among authors: glabe cg. Biochem Biophys Res Commun. 2016 Sep 2;477(4):700-705. doi: 10.1016/j.bbrc.2016.06.122. Epub 2016 Jun 27. Biochem Biophys Res Commun. 2016. PMID: 27363332 Free PMC article.

9

Soluble amyloid Abeta-(1-40) exists as a stable dimer at low concentrations.

Garzon-Rodriguez W, Sepulveda-Becerra M, Milton S, Glabe CG. Garzon-Rodriguez W, et al. Among authors: glabe cg. J Biol Chem. 1997 Aug 22;272(34):21037-44. doi: 10.1074/jbc.272.34.21037. J Biol Chem. 1997. PMID: 9261105 Free article.

10

Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis.

Kayed R, Head E, Thompson JL, McIntire TM, Milton SC, Cotman CW, Glabe CG. Kayed R, et al. Among authors: glabe cg. Science. 2003 Apr 18;300(5618):486-9. doi: 10.1126/science.1079469. Science. 2003. PMID: 12702875

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