Deng Y - Search Results

1

Fast analysis using monolithic columns coupled with high-flow on-line extraction and electrospray mass spectrometric detection for the direct and simultaneous quantitation of multiple components in plasma.

Zeng H, Deng Y, Wu JT. Zeng H, et al. Among authors: deng y. J Chromatogr B Analyt Technol Biomed Life Sci. 2003 May 25;788(2):331-7. doi: 10.1016/s1570-0232(03)00040-0. J Chromatogr B Analyt Technol Biomed Life Sci. 2003. PMID: 12705973

2

High-speed gradient parallel liquid chromatography/tandem mass spectrometry with fully automated sample preparation for bioanalysis: 30 seconds per sample from plasma.

Deng Y, Wu JT, Lloyd TL, Chi CL, Olah TV, Unger SE. Deng Y, et al. Rapid Commun Mass Spectrom. 2002;16(11):1116-23. doi: 10.1002/rcm.688. Rapid Commun Mass Spectrom. 2002. PMID: 11992516

3

Quantitation of drug metabolites in the absence of pure metabolite standards by high-performance liquid chromatography coupled with a chemiluminescence nitrogen detector and mass spectrometer.

Deng Y, Wu JT, Zhang H, Olah TV. Deng Y, et al. Rapid Commun Mass Spectrom. 2004;18(15):1681-5. doi: 10.1002/rcm.1540. Rapid Commun Mass Spectrom. 2004. PMID: 15282765

4

Tandem mass spectrometry with online high-flow reversed-phase extraction and normal-phase chromatography on silica columns with aqueous-organic mobile phase for quantitation of polar compounds in biological fluids.

Deng Y, Zhang H, Wu JT, Olah TV. Deng Y, et al. Rapid Commun Mass Spectrom. 2005;19(20):2929-34. doi: 10.1002/rcm.2144. Rapid Commun Mass Spectrom. 2005. PMID: 16175657

5

High-speed liquid chromatography/tandem mass spectrometry using a monolithic column for high-throughput bioanalysis.

Wu JT, Zeng H, Deng Y, Unger SE. Wu JT, et al. Among authors: deng y. Rapid Commun Mass Spectrom. 2001;15(13):1113-9. doi: 10.1002/rcm.348. Rapid Commun Mass Spectrom. 2001. PMID: 11404848

6

Multiple-sprayer tandem mass spectrometry with parallel high flow extraction and parallel separation for high-throughput quantitation in biological fluids.

Deng Y, Zeng H, Unger SE, Wu JT. Deng Y, et al. Rapid Commun Mass Spectrom. 2001;15(17):1634-40. doi: 10.1002/rcm.422. Rapid Commun Mass Spectrom. 2001. PMID: 11544604

7

N-in-1 dosing pharmacokinetics in drug discovery: experience, theoretical and practical considerations.

He K, Qian M, Wong H, Bai SA, He B, Brogdon B, Grace JE, Xin B, Wu J, Ren SX, Zeng H, Deng Y, Graden DM, Olah TV, Unger SE, Luettgen JM, Knabb RM, Pinto DJ, Lam PY, Duan J, Wexler RR, Decicco CP, Christ DD, Grossman SJ. He K, et al. Among authors: deng y. J Pharm Sci. 2008 Jul;97(7):2568-80. doi: 10.1002/jps.21196. J Pharm Sci. 2008. PMID: 17914718

8

Pharmacokinetics and pharmacodynamics of DPC 333 ((2R)-2-((3R)-3-amino-3{4-[2-methyl-4-quinolinyl) methoxy] phenyl}-2-oxopyrrolidinyl)-N-hydroxy-4-methylpentanamide)), a potent and selective inhibitor of tumor necrosis factor alpha-converting enzyme in rodents, dogs, chimpanzees, and humans.

Qian M, Bai SA, Brogdon B, Wu JT, Liu RQ, Covington MB, Vaddi K, Newton RC, Fossler MJ, Garner CE, Deng Y, Maduskuie T, Trzaskos J, Duan JJ, Decicco CP, Christ DD. Qian M, et al. Among authors: deng y. Drug Metab Dispos. 2007 Oct;35(10):1916-25. doi: 10.1124/dmd.107.015933. Epub 2007 Jul 26. Drug Metab Dispos. 2007. PMID: 17656469 Clinical Trial.

9

Development and validation of sensitive and selective LC-MS/MS methods for the determination of BMS-708163, a gamma-secretase inhibitor, in plasma and cerebrospinal fluid using deprotonated or formate adduct ions as precursor ions.

Gu H, Deng Y, Wang J, Aubry AF, Arnold ME. Gu H, et al. Among authors: deng y. J Chromatogr B Analyt Technol Biomed Life Sci. 2010 Sep 1;878(25):2319-26. doi: 10.1016/j.jchromb.2010.06.041. Epub 2010 Jul 6. J Chromatogr B Analyt Technol Biomed Life Sci. 2010. PMID: 20674522

10

A rugged and accurate liquid chromatography-tandem mass spectrometry method for quantitative determination of BMS-790052 in plasma.

Jiang H, Zeng J, Deng Y, Xia YQ, Ouyang Z, Jemal M, Salcedo TW, Arnold ME. Jiang H, et al. Among authors: deng y. J Chromatogr B Analyt Technol Biomed Life Sci. 2011 Jul 15;879(22):2064-72. doi: 10.1016/j.jchromb.2011.05.036. Epub 2011 May 30. J Chromatogr B Analyt Technol Biomed Life Sci. 2011. PMID: 21704571

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