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Page 1
Rb is critical in a mammalian tissue stem cell population.
Wenzel PL, Wu L, de Bruin A, Chong JL, Chen WY, Dureska G, Sites E, Pan T, Sharma A, Huang K, Ridgway R, Mosaliganti K, Sharp R, Machiraju R, Saltz J, Yamamoto H, Cross JC, Robinson ML, Leone G. Wenzel PL, et al. Among authors: leone g. Genes Dev. 2007 Jan 1;21(1):85-97. doi: 10.1101/gad.1485307. Genes Dev. 2007. PMID: 17210791 Free PMC article.
Extra-embryonic function of Rb is essential for embryonic development and viability.
Wu L, de Bruin A, Saavedra HI, Starovic M, Trimboli A, Yang Y, Opavska J, Wilson P, Thompson JC, Ostrowski MC, Rosol TJ, Woollett LA, Weinstein M, Cross JC, Robinson ML, Leone G. Wu L, et al. Among authors: leone g. Nature. 2003 Feb 27;421(6926):942-7. doi: 10.1038/nature01417. Nature. 2003. PMID: 12607001
Aberrant regulation of survivin by the RB/E2F family of proteins.
Jiang Y, Saavedra HI, Holloway MP, Leone G, Altura RA. Jiang Y, et al. Among authors: leone g. J Biol Chem. 2004 Sep 24;279(39):40511-20. doi: 10.1074/jbc.M404496200. Epub 2004 Jul 22. J Biol Chem. 2004. PMID: 15271987 Free article.
Allele-specific tumor spectrum in pten knockin mice.
Wang H, Karikomi M, Naidu S, Rajmohan R, Caserta E, Chen HZ, Rawahneh M, Moffitt J, Stephens JA, Fernandez SA, Weinstein M, Wang D, Sadee W, La Perle K, Stromberg P, Rosol TJ, Eng C, Ostrowski MC, Leone G. Wang H, et al. Among authors: leone g. Proc Natl Acad Sci U S A. 2010 Mar 16;107(11):5142-7. doi: 10.1073/pnas.0912524107. Epub 2010 Mar 1. Proc Natl Acad Sci U S A. 2010. PMID: 20194734 Free PMC article.
The E2F1-3 transcription factors are essential for cellular proliferation.
Wu L, Timmers C, Maiti B, Saavedra HI, Sang L, Chong GT, Nuckolls F, Giangrande P, Wright FA, Field SJ, Greenberg ME, Orkin S, Nevins JR, Robinson ML, Leone G. Wu L, et al. Among authors: leone g. Nature. 2001 Nov 22;414(6862):457-62. doi: 10.1038/35106593. Nature. 2001. PMID: 11719808
1,355 results