Gorski JC - Search Results

1

Pharmacokinetics and QT interval pharmacodynamics of oral haloperidol in poor and extensive metabolizers of CYP2D6.

Desai M, Tanus-Santos JE, Li L, Gorski JC, Arefayene M, Liu Y, Desta Z, Flockhart DA. Desai M, et al. Among authors: gorski jc. Pharmacogenomics J. 2003;3(2):105-13. doi: 10.1038/sj.tpj.6500160. Pharmacogenomics J. 2003. PMID: 12746736 Clinical Trial.

2

Effect of cirrhosis and liver transplantation on the gender difference in QT interval.

Adigun AQ, Pinto AG, Flockhart DA, Gorski JC, Li L, Hall SD, Chalasani N. Adigun AQ, et al. Among authors: gorski jc. Am J Cardiol. 2005 Mar 1;95(5):691-4. doi: 10.1016/j.amjcard.2004.10.054. Am J Cardiol. 2005. PMID: 15721125

3

The cytochrome P450 2B6 (CYP2B6) is the main catalyst of efavirenz primary and secondary metabolism: implication for HIV/AIDS therapy and utility of efavirenz as a substrate marker of CYP2B6 catalytic activity.

Ward BA, Gorski JC, Jones DR, Hall SD, Flockhart DA, Desta Z. Ward BA, et al. Among authors: gorski jc. J Pharmacol Exp Ther. 2003 Jul;306(1):287-300. doi: 10.1124/jpet.103.049601. Epub 2003 Apr 3. J Pharmacol Exp Ther. 2003. PMID: 12676886

4

Dextromethorphan to dextrorphan urinary metabolic ratio does not reflect dextromethorphan oral clearance.

Borges S, Li L, Hamman MA, Jones DR, Hall SD, Gorski JC. Borges S, et al. Among authors: gorski jc. Drug Metab Dispos. 2005 Jul;33(7):1052-5. doi: 10.1124/dmd.104.003459. Epub 2005 Apr 8. Drug Metab Dispos. 2005. PMID: 15821042

5

Inhibition of human intestinal wall metabolism by macrolide antibiotics: effect of clarithromycin on cytochrome P450 3A4/5 activity and expression.

Pinto AG, Wang YH, Chalasani N, Skaar T, Kolwankar D, Gorski JC, Liangpunsakul S, Hamman MA, Arefayene M, Hall SD. Pinto AG, et al. Among authors: gorski jc. Clin Pharmacol Ther. 2005 Mar;77(3):178-88. doi: 10.1016/j.clpt.2004.10.002. Clin Pharmacol Ther. 2005. PMID: 15735612 Clinical Trial.

6

Intramuscular haloperidol or lorazepam and QT intervals in schizophrenia.

Harvey AT, Flockhart D, Gorski JC, Greenblatt DJ, Burke M, Werder S, Preskorn SH. Harvey AT, et al. Among authors: gorski jc. J Clin Pharmacol. 2004 Oct;44(10):1173-84. doi: 10.1177/0091270004267807. J Clin Pharmacol. 2004. PMID: 15342619 Clinical Trial.

7

The effect of echinacea (Echinacea purpurea root) on cytochrome P450 activity in vivo.

Gorski JC, Huang SM, Pinto A, Hamman MA, Hilligoss JK, Zaheer NA, Desai M, Miller M, Hall SD. Gorski JC, et al. Clin Pharmacol Ther. 2004 Jan;75(1):89-100. doi: 10.1016/j.clpt.2003.09.013. Clin Pharmacol Ther. 2004. PMID: 14749695

8

Diabetes mellitus increases the in vivo activity of cytochrome P450 2E1 in humans.

Wang Z, Hall SD, Maya JF, Li L, Asghar A, Gorski JC. Wang Z, et al. Among authors: gorski jc. Br J Clin Pharmacol. 2003 Jan;55(1):77-85. doi: 10.1046/j.1365-2125.2003.01731.x. Br J Clin Pharmacol. 2003. PMID: 12534643 Free PMC article.

9

Physiologically based pharmacokinetic model of mechanism-based inhibition of CYP3A by clarithromycin.

Quinney SK, Zhang X, Lucksiri A, Gorski JC, Li L, Hall SD. Quinney SK, et al. Among authors: gorski jc. Drug Metab Dispos. 2010 Feb;38(2):241-8. doi: 10.1124/dmd.109.028746. Epub 2009 Nov 2. Drug Metab Dispos. 2010. PMID: 19884323 Free PMC article.

10

In vivo effects of interleukin-10 on human cytochrome P450 activity.

Gorski JC, Hall SD, Becker P, Affrime MB, Cutler DL, Haehner-Daniels B. Gorski JC, et al. Clin Pharmacol Ther. 2000 Jan;67(1):32-43. doi: 10.1067/mcp.2000.103860. Clin Pharmacol Ther. 2000. PMID: 10668851 Clinical Trial.

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