Metcalfe JC - Search Results

1

A transforming growth factorbeta1 signal peptide variant increases secretion in vitro and is associated with increased incidence of invasive breast cancer.

Dunning AM, Ellis PD, McBride S, Kirschenlohr HL, Healey CS, Kemp PR, Luben RN, Chang-Claude J, Mannermaa A, Kataja V, Pharoah PD, Easton DF, Ponder BA, Metcalfe JC. Dunning AM, et al. Among authors: metcalfe jc. Cancer Res. 2003 May 15;63(10):2610-5. Cancer Res. 2003. PMID: 12750287

2

TGF-β signaling pathway and breast cancer susceptibility.

Scollen S, Luccarini C, Baynes C, Driver K, Humphreys MK, Garcia-Closas M, Figueroa J, Lissowska J, Pharoah PD, Easton DF, Hesketh R, Metcalfe JC, Dunning AM. Scollen S, et al. Among authors: metcalfe jc. Cancer Epidemiol Biomarkers Prev. 2011 Jun;20(6):1112-9. doi: 10.1158/1055-9965.EPI-11-0062. Epub 2011 Apr 28. Cancer Epidemiol Biomarkers Prev. 2011. PMID: 21527583 Free PMC article. Clinical Trial.

3

Inhibiting mutations in the transforming growth factor beta type 2 receptor in recurrent human breast cancer.

Lücke CD, Philpott A, Metcalfe JC, Thompson AM, Hughes-Davies L, Kemp PR, Hesketh R. Lücke CD, et al. Among authors: metcalfe jc. Cancer Res. 2001 Jan 15;61(2):482-5. Cancer Res. 2001. PMID: 11212236

4

Proliferation of human aortic vascular smooth muscle cells in culture is modulated by active TGF beta.

Kirschenlohr HL, Metcalfe JC, Weissberg PL, Grainger DJ. Kirschenlohr HL, et al. Among authors: metcalfe jc. Cardiovasc Res. 1995 Jun;29(6):848-55. Cardiovasc Res. 1995. PMID: 7656289

5

Activation of transforming growth factor-beta is inhibited in transgenic apolipoprotein(a) mice.

Grainger DJ, Kemp PR, Liu AC, Lawn RM, Metcalfe JC. Grainger DJ, et al. Among authors: metcalfe jc. Nature. 1994 Aug 11;370(6489):460-2. doi: 10.1038/370460a0. Nature. 1994. PMID: 8047165

6

Adult human aortic smooth muscle cells in culture produce active TGF-beta.

Kirschenlohr HL, Metcalfe JC, Weissberg PL, Grainger DJ. Kirschenlohr HL, et al. Among authors: metcalfe jc. Am J Physiol. 1993 Aug;265(2 Pt 1):C571-6. doi: 10.1152/ajpcell.1993.265.2.C571. Am J Physiol. 1993. PMID: 8368284

7

Adhesion of endothelial cells to NOV is mediated by the integrins alphavbeta3 and alpha5beta1.

Ellis PD, Metcalfe JC, Hyvönen M, Kemp PR. Ellis PD, et al. Among authors: metcalfe jc. J Vasc Res. 2003 May-Jun;40(3):234-43. doi: 10.1159/000071887. J Vasc Res. 2003. PMID: 12902636

8

Selective modulation of the SM22alpha promoter by the binding of BTEB3 (basal transcription element-binding protein 3) to TGGG repeats.

Martin KM, Ellis PD, Metcalfe JC, Kemp PR. Martin KM, et al. Among authors: metcalfe jc. Biochem J. 2003 Oct 15;375(Pt 2):457-63. doi: 10.1042/BJ20030870. Biochem J. 2003. PMID: 12848620 Free PMC article.

9

The serum concentration of active transforming growth factor-beta is severely depressed in advanced atherosclerosis.

Grainger DJ, Kemp PR, Metcalfe JC, Liu AC, Lawn RM, Williams NR, Grace AA, Schofield PM, Chauhan A. Grainger DJ, et al. Among authors: metcalfe jc. Nat Med. 1995 Jan;1(1):74-9. doi: 10.1038/nm0195-74. Nat Med. 1995. PMID: 7584958

10

Transforming growth factor beta decreases the rate of proliferation of rat vascular smooth muscle cells by extending the G2 phase of the cell cycle and delays the rise in cyclic AMP before entry into M phase.

Grainger DJ, Kemp PR, Witchell CM, Weissberg PL, Metcalfe JC. Grainger DJ, et al. Among authors: metcalfe jc. Biochem J. 1994 Apr 1;299 ( Pt 1)(Pt 1):227-35. doi: 10.1042/bj2990227. Biochem J. 1994. PMID: 8166645 Free PMC article.

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