Ayers JT - Search Results

1

N-n-alkylpyridinium analogs, a novel class of nicotinic receptor antagonists: selective inhibition of nicotine-evoked [3H] dopamine overflow from superfused rat striatal slices.

Grinevich VP, Crooks PA, Sumithran SP, Haubner AJ, Ayers JT, Dwoskin LP. Grinevich VP, et al. Among authors: ayers jt. J Pharmacol Exp Ther. 2003 Sep;306(3):1011-20. doi: 10.1124/jpet.103.051789. Epub 2003 May 23. J Pharmacol Exp Ther. 2003. PMID: 12766255

2

N-n-alkylnicotinium analogs, a novel class of nicotinic receptor antagonist: inhibition of S(-)-nicotine-evoked [(3)H]dopamine overflow from superfused rat striatal slices.

Wilkins LH Jr, Haubner A, Ayers JT, Crooks PA, Dwoskin LP. Wilkins LH Jr, et al. Among authors: ayers jt. J Pharmacol Exp Ther. 2002 Jun;301(3):1088-96. doi: 10.1124/jpet.301.3.1088. J Pharmacol Exp Ther. 2002. PMID: 12023541

3

bis-Azaaromatic quaternary ammonium analogues: ligands for alpha4beta2* and alpha7* subtypes of neuronal nicotinic receptors.

Ayers JT, Dwoskin LP, Deaciuc AG, Grinevich VP, Zhu J, Crooks PA. Ayers JT, et al. Bioorg Med Chem Lett. 2002 Nov 4;12(21):3067-71. doi: 10.1016/s0960-894x(02)00687-x. Bioorg Med Chem Lett. 2002. PMID: 12372503

4

N-n-alkylnicotinium analogs, a novel class of nicotinic receptor antagonists: interaction with alpha4beta2* and alpha7* neuronal nicotinic receptors.

Wilkins LH Jr, Grinevich VP, Ayers JT, Crooks PA, Dwoskin LP. Wilkins LH Jr, et al. Among authors: ayers jt. J Pharmacol Exp Ther. 2003 Jan;304(1):400-10. doi: 10.1124/jpet.102.043349. J Pharmacol Exp Ther. 2003. PMID: 12490617

5

Subtype-selective nicotinic receptor antagonists: potential as tobacco use cessation agents.

Dwoskin LP, Sumithran SP, Zhu J, Deaciuc AG, Ayers JT, Crooks PA. Dwoskin LP, et al. Among authors: ayers jt. Bioorg Med Chem Lett. 2004 Apr 19;14(8):1863-7. doi: 10.1016/j.bmcl.2003.10.073. Bioorg Med Chem Lett. 2004. PMID: 15050617

6

Development of subtype-selective ligands as antagonists at nicotinic receptors mediating nicotine-evoked dopamine release.

Crooks PA, Ayers JT, Xu R, Sumithran SP, Grinevich VP, Wilkins LH, Deaciuc AG, Allen DD, Dwoskin LP. Crooks PA, et al. Among authors: ayers jt. Bioorg Med Chem Lett. 2004 Apr 19;14(8):1869-74. doi: 10.1016/j.bmcl.2003.10.074. Bioorg Med Chem Lett. 2004. PMID: 15050618

7

QSAR modeling of mono- and bis-quaternary ammonium salts that act as antagonists at neuronal nicotinic acetylcholine receptors mediating dopamine release.

Zheng F, Bayram E, Sumithran SP, Ayers JT, Zhan CG, Schmitt JD, Dwoskin LP, Crooks PA. Zheng F, et al. Among authors: ayers jt. Bioorg Med Chem. 2006 May 1;14(9):3017-37. doi: 10.1016/j.bmc.2005.12.036. Epub 2006 Jan 20. Bioorg Med Chem. 2006. PMID: 16431111

8

N-n-alkylnicotinium analogs, a novel class of antagonists at alpha 4 beta 2* nicotinic acetylcholine receptors: inhibition of S(-)-nicotine-evoked 86Rb+ efflux from rat thalamic synaptosomes.

Wilkins LH Jr, Miller DK, Ayers JT, Crooks PA, Dwoskin LP. Wilkins LH Jr, et al. Among authors: ayers jt. AAPS J. 2006 Jan 13;7(4):E922-30. doi: 10.1208/aapsj070490. AAPS J. 2006. PMID: 16594645 Free PMC article.

9

N,N'-Alkane-diyl-bis-3-picoliniums as nicotinic receptor antagonists: inhibition of nicotine-evoked dopamine release and hyperactivity.

Dwoskin LP, Wooters TE, Sumithran SP, Siripurapu KB, Joyce BM, Lockman PR, Manda VK, Ayers JT, Zhang Z, Deaciuc AG, McIntosh JM, Crooks PA, Bardo MT. Dwoskin LP, et al. Among authors: ayers jt. J Pharmacol Exp Ther. 2008 Aug;326(2):563-76. doi: 10.1124/jpet.108.136630. Epub 2008 May 6. J Pharmacol Exp Ther. 2008. PMID: 18460644 Free PMC article.

10

Molecular modeling of mono- and bis-quaternary ammonium salts as ligands at the alpha4beta2 nicotinic acetylcholine receptor subtype using nonlinear techniques.

Ayers JT, Clauset A, Schmitt JD, Dwoskin LP, Crooks PA. Ayers JT, et al. AAPS J. 2005 Oct 25;7(3):E678-85. doi: 10.1208/aapsj070368. AAPS J. 2005. PMID: 16353944 Free PMC article.

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