Freel Meyers CL - Search Results

1

Walsh CT, Losey HC, Freel Meyers CL. Walsh CT, et al. Among authors: freel meyers cl. Biochem Soc Trans. 2003 Jun;31(Pt 3):487-92. doi: 10.1042/bst0310487. Biochem Soc Trans. 2003. PMID: 12773141 Review.

2

Initial characterization of novobiocic acid noviosyl transferase activity of NovM in biosynthesis of the antibiotic novobiocin.

Freel Meyers CL, Oberthür M, Anderson JW, Kahne D, Walsh CT. Freel Meyers CL, et al. Biochemistry. 2003 Apr 15;42(14):4179-89. doi: 10.1021/bi0340088. Biochemistry. 2003. PMID: 12680772

3

Antibiotic glycosyltransferases: antibiotic maturation and prospects for reprogramming.

Walsh C, Freel Meyers CL, Losey HC. Walsh C, et al. Among authors: freel meyers cl. J Med Chem. 2003 Jul 31;46(16):3425-36. doi: 10.1021/jm030257i. J Med Chem. 2003. PMID: 12877577 Review. No abstract available.

4

Assembly of dimeric variants of coumermycins by tandem action of the four biosynthetic enzymes CouL, CouM, CouP, and NovN.

Freel Meyers CL, Oberthür M, Heide L, Kahne D, Walsh CT. Freel Meyers CL, et al. Biochemistry. 2004 Nov 30;43(47):15022-36. doi: 10.1021/bi048457z. Biochemistry. 2004. PMID: 15554710

5

Characterization of the aminocoumarin ligase SimL from the simocyclinone pathway and tandem incubation with NovM,P,N from the novobiocin pathway.

Pacholec M, Freel Meyers CL, Oberthür M, Kahne D, Walsh CT. Pacholec M, et al. Among authors: freel meyers cl. Biochemistry. 2005 Mar 29;44(12):4949-56. doi: 10.1021/bi047303g. Biochemistry. 2005. PMID: 15779922

6

Crystallization and preliminary X-ray analysis of the O-methyltransferase NovP from the novobiocin-biosynthetic cluster of Streptomyces spheroides.

Stevenson CE, Freel Meyers CL, Walsh CT, Lawson DM. Stevenson CE, et al. Among authors: freel meyers cl. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Mar 1;63(Pt 3):236-8. doi: 10.1107/S1744309107008287. Epub 2007 Feb 28. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007. PMID: 17329822 Free PMC article.

7

Crystallization and preliminary X-ray analysis of the O-carbamoyltransferase NovN from the novobiocin-biosynthetic cluster of Streptomyces spheroides.

Gómez García I, Freel Meyers CL, Walsh CT, Lawson DM. Gómez García I, et al. Among authors: freel meyers cl. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2008 Nov 1;64(Pt 11):1000-2. doi: 10.1107/S1744309108030145. Epub 2008 Oct 25. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2008. PMID: 18997325 Free PMC article.

8

The crystal structure of the novobiocin biosynthetic enzyme NovP: the first representative structure for the TylF O-methyltransferase superfamily.

Gómez García I, Stevenson CE, Usón I, Freel Meyers CL, Walsh CT, Lawson DM. Gómez García I, et al. Among authors: freel meyers cl. J Mol Biol. 2010 Jan 15;395(2):390-407. doi: 10.1016/j.jmb.2009.10.045. Epub 2009 Oct 24. J Mol Biol. 2010. PMID: 19857499 Free PMC article.

9

Characterization of NovP and NovN: completion of novobiocin biosynthesis by sequential tailoring of the noviosyl ring.

Freel Meyers CL, Oberthür M, Xu H, Heide L, Kahne D, Walsh CT. Freel Meyers CL, et al. Angew Chem Int Ed Engl. 2004 Jan;43(1):67-70. doi: 10.1002/anie.200352626. Angew Chem Int Ed Engl. 2004. PMID: 14694473 No abstract available.

10

Crystallization and preliminary X-ray studies on the putative dTDP sugar epimerase NovW from the novobiocin biosynthetic cluster of Streptomyces spheroides.

Jakimowicz P, Freel Meyers CL, Walsh CT, Buttner MJ, Lawson DM. Jakimowicz P, et al. Among authors: freel meyers cl. Acta Crystallogr D Biol Crystallogr. 2003 Aug;59(Pt 8):1507-9. doi: 10.1107/s0907444903012848. Epub 2003 Jul 23. Acta Crystallogr D Biol Crystallogr. 2003. PMID: 12876368

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