Segatto O - Search Results

1

Feedback inhibition by RALT controls signal output by the ErbB network.

Anastasi S, Fiorentino L, Fiorini M, Fraioli R, Sala G, Castellani L, Alemà S, Alimandi M, Segatto O. Anastasi S, et al. Among authors: segatto o. Oncogene. 2003 Jul 3;22(27):4221-34. doi: 10.1038/sj.onc.1206516. Oncogene. 2003. PMID: 12833145

2

Expression of RALT, a feedback inhibitor of ErbB receptors, is subjected to an integrated transcriptional and post-translational control.

Fiorini M, Ballarò C, Sala G, Falcone G, Alemà S, Segatto O. Fiorini M, et al. Among authors: segatto o. Oncogene. 2002 Sep 19;21(42):6530-9. doi: 10.1038/sj.onc.1205823. Oncogene. 2002. PMID: 12226756

3

Loss of RALT/MIG-6 expression in ERBB2-amplified breast carcinomas enhances ErbB-2 oncogenic potency and favors resistance to Herceptin.

Anastasi S, Sala G, Huiping C, Caprini E, Russo G, Iacovelli S, Lucini F, Ingvarsson S, Segatto O. Anastasi S, et al. Among authors: segatto o. Oncogene. 2005 Jun 30;24(28):4540-8. doi: 10.1038/sj.onc.1208658. Oncogene. 2005. PMID: 15856022

4

A two-tiered mechanism of EGFR inhibition by RALT/MIG6 via kinase suppression and receptor degradation.

Frosi Y, Anastasi S, Ballarò C, Varsano G, Castellani L, Maspero E, Polo S, Alemà S, Segatto O. Frosi Y, et al. Among authors: segatto o. J Cell Biol. 2010 May 3;189(3):557-71. doi: 10.1083/jcb.201002032. Epub 2010 Apr 26. J Cell Biol. 2010. PMID: 20421427 Free PMC article.

5

Regulation of epidermal growth factor receptor signalling by inducible feedback inhibitors.

Segatto O, Anastasi S, Alemà S. Segatto O, et al. J Cell Sci. 2011 Jun 1;124(Pt 11):1785-93. doi: 10.1242/jcs.083303. J Cell Sci. 2011. PMID: 21576352 Review.

6

Inhibition of ErbB-2 mitogenic and transforming activity by RALT, a mitogen-induced signal transducer which binds to the ErbB-2 kinase domain.

Fiorentino L, Pertica C, Fiorini M, Talora C, Crescenzi M, Castellani L, Alemà S, Benedetti P, Segatto O. Fiorentino L, et al. Among authors: segatto o. Mol Cell Biol. 2000 Oct;20(20):7735-50. doi: 10.1128/MCB.20.20.7735-7750.2000. Mol Cell Biol. 2000. PMID: 11003669 Free PMC article.

7

Negative regulation of receptor tyrosine kinase signals.

Fiorini M, Alimandi M, Fiorentino L, Sala G, Segatto O. Fiorini M, et al. Among authors: segatto o. FEBS Lett. 2001 Feb 16;490(3):132-41. doi: 10.1016/s0014-5793(01)02116-0. FEBS Lett. 2001. PMID: 11223028 Free article. Review.

8

The evolutionarily conserved EBR module of RALT/MIG6 mediates suppression of the EGFR catalytic activity.

Anastasi S, Baietti MF, Frosi Y, Alemà S, Segatto O. Anastasi S, et al. Among authors: segatto o. Oncogene. 2007 Dec 13;26(57):7833-46. doi: 10.1038/sj.onc.1210590. Epub 2007 Jun 18. Oncogene. 2007. PMID: 17599051

9

Regulation of the ErbB network by the MIG6 feedback loop in physiology, tumor suppression and responses to oncogene-targeted therapeutics.

Anastasi S, Lamberti D, Alemà S, Segatto O. Anastasi S, et al. Among authors: segatto o. Semin Cell Dev Biol. 2016 Feb;50:115-24. doi: 10.1016/j.semcdb.2015.10.001. Epub 2015 Oct 9. Semin Cell Dev Biol. 2016. PMID: 26456277 Review.

10

A pervasive role for MIG6 in restraining cell proliferation.

Anastasi S, Castellani L, Alemà S, Segatto O. Anastasi S, et al. Among authors: segatto o. Cell Death Differ. 2014 Mar;21(3):345-7. doi: 10.1038/cdd.2013.182. Epub 2013 Dec 20. Cell Death Differ. 2014. PMID: 24362438 Free PMC article. No abstract available.

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