Withers SG - Search Results

1

Family 39 alpha-l-iduronidases and beta-D-xylosidases react through similar glycosyl-enzyme intermediates: identification of the human iduronidase nucleophile.

Nieman CE, Wong AW, He S, Clarke L, Hopwood JJ, Withers SG. Nieman CE, et al. Among authors: withers sg. Biochemistry. 2003 Jul 8;42(26):8054-65. doi: 10.1021/bi034293v. Biochemistry. 2003. PMID: 12834357

2

Glu-537, not Glu-461, is the nucleophile in the active site of (lac Z) beta-galactosidase from Escherichia coli.

Gebler JC, Aebersold R, Withers SG. Gebler JC, et al. Among authors: withers sg. J Biol Chem. 1992 Jun 5;267(16):11126-30. J Biol Chem. 1992. PMID: 1350782 Free article.

3

Mechanistic consequences of mutation of the active site nucleophile Glu 358 in Agrobacterium beta-glucosidase.

Withers SG, Rupitz K, Trimbur D, Warren RA. Withers SG, et al. Biochemistry. 1992 Oct 20;31(41):9979-85. doi: 10.1021/bi00156a017. Biochemistry. 1992. PMID: 1356439

4

Mechanism of Agrobacterium beta-glucosidase: kinetic studies.

Kempton JB, Withers SG. Kempton JB, et al. Among authors: withers sg. Biochemistry. 1992 Oct 20;31(41):9961-9. doi: 10.1021/bi00156a015. Biochemistry. 1992. PMID: 1390780

5

Inactivation of a beta-glucosidase through the accumulation of a stable 2-deoxy-2-fluoro-alpha-D-glucopyranosyl-enzyme intermediate: a detailed investigation.

Street IP, Kempton JB, Withers SG. Street IP, et al. Among authors: withers sg. Biochemistry. 1992 Oct 20;31(41):9970-8. doi: 10.1021/bi00156a016. Biochemistry. 1992. PMID: 1390781

6

Binding energy and catalysis: deoxyfluoro sugars as probes of hydrogen bonding in phosphoglucomutase.

Percival MD, Withers SG. Percival MD, et al. Among authors: withers sg. Biochemistry. 1992 Jan 21;31(2):498-505. doi: 10.1021/bi00117a028. Biochemistry. 1992. PMID: 1531025

7

19F NMR investigations of the catalytic mechanism of phosphoglucomutase using fluorinated substrates and inhibitors.

Percival MD, Withers SG. Percival MD, et al. Among authors: withers sg. Biochemistry. 1992 Jan 21;31(2):505-12. doi: 10.1021/bi00117a029. Biochemistry. 1992. PMID: 1531026

8

Reassessment of the catalytic mechanism of glycogen debranching enzyme.

Liu W, Madsen NB, Braun C, Withers SG. Liu W, et al. Among authors: withers sg. Biochemistry. 1991 Feb 5;30(5):1419-24. doi: 10.1021/bi00219a036. Biochemistry. 1991. PMID: 1991122

9

Measurement of active-site homology between potato and rabbit muscle alpha-glucan phosphorylases through use of a linear free energy relationship.

Withers SG, Rupitz K. Withers SG, et al. Biochemistry. 1990 Jul 10;29(27):6405-9. doi: 10.1021/bi00479a010. Biochemistry. 1990. PMID: 2207081

10

Fluorinated and deoxygenated substrates as probes of transition-state structure in glycogen phosphorylase.

Street IP, Rupitz K, Withers SG. Street IP, et al. Among authors: withers sg. Biochemistry. 1989 Feb 21;28(4):1581-7. doi: 10.1021/bi00430a024. Biochemistry. 1989. PMID: 2719921

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