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Page 1
Quantitative gene expression profiling of mouse brain regions reveals differential transcripts conserved in human and affected in disease models.
Brochier C, Gaillard MC, Diguet E, Caudy N, Dossat C, Ségurens B, Wincker P, Roze E, Caboche J, Hantraye P, Brouillet E, Elalouf JM, de Chaldée M. Brochier C, et al. Among authors: hantraye p. Physiol Genomics. 2008 Apr 22;33(2):170-9. doi: 10.1152/physiolgenomics.00125.2007. Epub 2008 Feb 5. Physiol Genomics. 2008. PMID: 18252803
Dopamine determines the vulnerability of striatal neurons to the N-terminal fragment of mutant huntingtin through the regulation of mitochondrial complex II.
Benchoua A, Trioulier Y, Diguet E, Malgorn C, Gaillard MC, Dufour N, Elalouf JM, Krajewski S, Hantraye P, Déglon N, Brouillet E. Benchoua A, et al. Among authors: hantraye p. Hum Mol Genet. 2008 May 15;17(10):1446-56. doi: 10.1093/hmg/ddn033. Epub 2008 Feb 11. Hum Mol Genet. 2008. PMID: 18267960 Free PMC article.
Striatal long noncoding RNA Abhd11os is neuroprotective against an N-terminal fragment of mutant huntingtin in vivo.
Francelle L, Galvan L, Gaillard MC, Petit F, Bernay B, Guillermier M, Bonvento G, Dufour N, Elalouf JM, Hantraye P, Déglon N, de Chaldée M, Brouillet E. Francelle L, et al. Among authors: hantraye p. Neurobiol Aging. 2015 Mar;36(3):1601.e7-16. doi: 10.1016/j.neurobiolaging.2014.11.014. Epub 2014 Dec 18. Neurobiol Aging. 2015. PMID: 25619660 Free article.
Normal aging modulates the neurotoxicity of mutant huntingtin.
Diguet E, Petit F, Escartin C, Cambon K, Bizat N, Dufour N, Hantraye P, Déglon N, Brouillet E. Diguet E, et al. Among authors: hantraye p. PLoS One. 2009;4(2):e4637. doi: 10.1371/journal.pone.0004637. Epub 2009 Feb 27. PLoS One. 2009. PMID: 19247483 Free PMC article.
Loss of the thyroid hormone-binding protein Crym renders striatal neurons more vulnerable to mutant huntingtin in Huntington's disease.
Francelle L, Galvan L, Gaillard MC, Guillermier M, Houitte D, Bonvento G, Petit F, Jan C, Dufour N, Hantraye P, Elalouf JM, De Chaldée M, Déglon N, Brouillet E. Francelle L, et al. Among authors: hantraye p. Hum Mol Genet. 2015 Mar 15;24(6):1563-73. doi: 10.1093/hmg/ddu571. Epub 2014 Nov 14. Hum Mol Genet. 2015. PMID: 25398949 Free PMC article.
mRNA trans-splicing in gene therapy for genetic diseases.
Berger A, Maire S, Gaillard MC, Sahel JA, Hantraye P, Bemelmans AP. Berger A, et al. Among authors: hantraye p. Wiley Interdiscip Rev RNA. 2016 Jul;7(4):487-98. doi: 10.1002/wrna.1347. Epub 2016 Mar 28. Wiley Interdiscip Rev RNA. 2016. PMID: 27018401 Free PMC article. Review.
The striatal kinase DCLK3 produces neuroprotection against mutant huntingtin.
Galvan L, Francelle L, Gaillard MC, de Longprez L, Carrillo-de Sauvage MA, Liot G, Cambon K, Stimmer L, Luccantoni S, Flament J, Valette J, de Chaldée M, Auregan G, Guillermier M, Joséphine C, Petit F, Jan C, Jarrige M, Dufour N, Bonvento G, Humbert S, Saudou F, Hantraye P, Merienne K, Bemelmans AP, Perrier AL, Déglon N, Brouillet E. Galvan L, et al. Among authors: hantraye p. Brain. 2018 May 1;141(5):1434-1454. doi: 10.1093/brain/awy057. Brain. 2018. PMID: 29534157 Free PMC article.
243 results