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Delivery to the central nervous system of a nonreplicative herpes simplex type 1 vector engineered with the interleukin 4 gene protects rhesus monkeys from hyperacute autoimmune encephalomyelitis.
Poliani PL, Brok H, Furlan R, Ruffini F, Bergami A, Desina G, Marconi PC, Rovaris M, Uccelli A, Glorioso JC, Penna G, Adorini L, Comi G, 't Hart B, Martino G. Poliani PL, et al. Among authors: adorini l. Hum Gene Ther. 2001 May 20;12(8):905-20. doi: 10.1089/104303401750195872. Hum Gene Ther. 2001. PMID: 11387056
Intrathecal delivery of IFN-gamma protects C57BL/6 mice from chronic-progressive experimental autoimmune encephalomyelitis by increasing apoptosis of central nervous system-infiltrating lymphocytes.
Furlan R, Brambilla E, Ruffini F, Poliani PL, Bergami A, Marconi PC, Franciotta DM, Penna G, Comi G, Adorini L, Martino G. Furlan R, et al. Among authors: adorini l. J Immunol. 2001 Aug 1;167(3):1821-9. doi: 10.4049/jimmunol.167.3.1821. J Immunol. 2001. PMID: 11466408
334 results