Huang Y - Search Results

1

A novel polyamine analog inhibits growth and induces apoptosis in human breast cancer cells.

Huang Y, Hager ER, Phillips DL, Dunn VR, Hacker A, Frydman B, Kink JA, Valasinas AL, Reddy VK, Marton LJ, Casero RA Jr, Davidson NE. Huang Y, et al. Clin Cancer Res. 2003 Jul;9(7):2769-77. Clin Cancer Res. 2003. PMID: 12855657 Free PMC article.

2

Polyamine analogs modulate gene expression by inhibiting lysine-specific demethylase 1 (LSD1) and altering chromatin structure in human breast cancer cells.

Zhu Q, Huang Y, Marton LJ, Woster PM, Davidson NE, Casero RA Jr. Zhu Q, et al. Among authors: huang y. Amino Acids. 2012 Feb;42(2-3):887-98. doi: 10.1007/s00726-011-1004-1. Epub 2011 Jul 30. Amino Acids. 2012. PMID: 21805138 Free PMC article.

3

Role of ornithine decarboxylase in regulation of estrogen receptor alpha expression and growth in human breast cancer cells.

Zhu Q, Jin L, Casero RA, Davidson NE, Huang Y. Zhu Q, et al. Among authors: huang y. Breast Cancer Res Treat. 2012 Nov;136(1):57-66. doi: 10.1007/s10549-012-2235-x. Epub 2012 Sep 14. Breast Cancer Res Treat. 2012. PMID: 22976807 Free PMC article.

4

Regulation of polyamine analogue cytotoxicity by c-Jun in human MDA-MB-435 cancer cells.

Huang Y, Keen JC, Hager E, Smith R, Hacker A, Frydman B, Valasinas AL, Reddy VK, Marton LJ, Casero RA Jr, Davidson NE. Huang Y, et al. Mol Cancer Res. 2004 Feb;2(2):81-8. Mol Cancer Res. 2004. PMID: 14985464

5

Molecular mechanisms of polyamine analogs in cancer cells.

Huang Y, Pledgie A, Casero RA Jr, Davidson NE. Huang Y, et al. Anticancer Drugs. 2005 Mar;16(3):229-41. doi: 10.1097/00001813-200503000-00002. Anticancer Drugs. 2005. PMID: 15711175 Review.

6

Role of p53/p21(Waf1/Cip1) in the regulation of polyamine analogue-induced growth inhibition and cell death in human breast cancer cells.

Huang Y, Pledgie A, Rubin E, Marton LJ, Woster PM, Sukumar S, Casero RA Jr, Davidson NE. Huang Y, et al. Cancer Biol Ther. 2005 Sep;4(9):1006-13. doi: 10.4161/cbt.4.9.1970. Epub 2005 Sep 23. Cancer Biol Ther. 2005. PMID: 16131835 Free PMC article.

7

Spermine oxidase SMO(PAOh1), Not N1-acetylpolyamine oxidase PAO, is the primary source of cytotoxic H2O2 in polyamine analogue-treated human breast cancer cell lines.

Pledgie A, Huang Y, Hacker A, Zhang Z, Woster PM, Davidson NE, Casero RA Jr. Pledgie A, et al. Among authors: huang y. J Biol Chem. 2005 Dec 2;280(48):39843-51. doi: 10.1074/jbc.M508177200. Epub 2005 Oct 5. J Biol Chem. 2005. PMID: 16207710 Free article.

8

Polyamine analogues down-regulate estrogen receptor alpha expression in human breast cancer cells.

Huang Y, Keen JC, Pledgie A, Marton LJ, Zhu T, Sukumar S, Park BH, Blair B, Brenner K, Casero RA Jr, Davidson NE. Huang Y, et al. J Biol Chem. 2006 Jul 14;281(28):19055-63. doi: 10.1074/jbc.M600910200. Epub 2006 May 4. J Biol Chem. 2006. PMID: 16679312 Free PMC article.

9

Novel oligoamine analogues inhibit lysine-specific demethylase 1 and induce reexpression of epigenetically silenced genes.

Huang Y, Stewart TM, Wu Y, Baylin SB, Marton LJ, Perkins B, Jones RJ, Woster PM, Casero RA Jr. Huang Y, et al. Clin Cancer Res. 2009 Dec 1;15(23):7217-28. doi: 10.1158/1078-0432.CCR-09-1293. Epub 2009 Nov 24. Clin Cancer Res. 2009. PMID: 19934284 Free PMC article.

10

Polyamine analogues targeting epigenetic gene regulation.

Huang Y, Marton LJ, Woster PM, Casero RA. Huang Y, et al. Essays Biochem. 2009 Nov 4;46:95-110. doi: 10.1042/bse0460007. Essays Biochem. 2009. PMID: 20095972 Free PMC article. Review.

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