Kowal D - Search Results

1

Characterization of the 5-HT6 receptor coupled to Ca2+ signaling using an enabling chimeric G-protein.

Zhang JY, Nawoschik S, Kowal D, Smith D, Spangler T, Ochalski R, Schechter L, Dunlop J. Zhang JY, et al. Among authors: kowal d. Eur J Pharmacol. 2003 Jul 4;472(1-2):33-8. doi: 10.1016/s0014-2999(03)01855-7. Eur J Pharmacol. 2003. PMID: 12860470

2

Distinct functional profiles of aripiprazole and olanzapine at RNA edited human 5-HT2C receptor isoforms.

Zhang JY, Kowal DM, Nawoschik SP, Lou Z, Dunlop J. Zhang JY, et al. Biochem Pharmacol. 2006 Feb 14;71(4):521-9. doi: 10.1016/j.bcp.2005.11.007. Epub 2005 Dec 5. Biochem Pharmacol. 2006. PMID: 16336943

3

The C-terminus of Gi family G-proteins as a determinant of 5-HT(1A) receptor coupling.

Kowal D, Zhang J, Nawoschik S, Ochalski R, Vlattas A, Shan Q, Schechter L, Dunlop J. Kowal D, et al. Biochem Biophys Res Commun. 2002 Jun 14;294(3):655-9. doi: 10.1016/S0006-291X(02)00535-1. Biochem Biophys Res Commun. 2002. PMID: 12056819

4

Functional calcium coupling with the human metabotropic glutamate receptor subtypes 2 and 4 by stable co-expression with a calcium pathway facilitating G-protein chimera in Chinese hamster ovary cells.

Kowal D, Nawoschik S, Ochalski R, Dunlop J. Kowal D, et al. Biochem Pharmacol. 2003 Sep 1;66(5):785-90. doi: 10.1016/s0006-2952(03)00399-x. Biochem Pharmacol. 2003. PMID: 12948859

5

A regiospecific synthesis of a series of 1-sulfonyl azepinoindoles as potent 5-HT6 ligands.

Liu KG, Lo JR, Comery TA, Zhang GM, Zhang JY, Kowal DM, Smith DL, Di L, Kerns EH, Schechter LE, Robichaud AJ. Liu KG, et al. Bioorg Med Chem Lett. 2008 Jul 15;18(14):3929-31. doi: 10.1016/j.bmcl.2008.06.030. Epub 2008 Jun 13. Bioorg Med Chem Lett. 2008. PMID: 18583130

6

Identification of a series of benzoxazoles as potent 5-HT6 ligands.

Liu KG, Lo JR, Comery TA, Zhang GM, Zhang JY, Kowal DM, Smith DL, Di L, Kerns EH, Schechter LE, Robichaud AJ. Liu KG, et al. Bioorg Med Chem Lett. 2009 Feb 15;19(4):1115-7. doi: 10.1016/j.bmcl.2008.12.107. Epub 2009 Jan 3. Bioorg Med Chem Lett. 2009. PMID: 19152787

7

1-Sulfonylindazoles as potent and selective 5-HT6 ligands.

Liu KG, Lo JR, Comery TA, Zhang GM, Zhang JY, Kowal DM, Smith DL, Di L, Kerns EH, Schechter LE, Robichaud AJ. Liu KG, et al. Bioorg Med Chem Lett. 2009 May 1;19(9):2413-5. doi: 10.1016/j.bmcl.2009.03.071. Epub 2009 Mar 21. Bioorg Med Chem Lett. 2009. PMID: 19345582

8

Identification of a novel series of 3-piperidinyl-5-sulfonylindazoles as potent 5-HT6 ligands.

Liu KG, Lo JR, Comery TA, Zhang GM, Zhang JY, Kowal DM, Smith DL, Di L, Kerns EH, Schechter LE, Robichaud AJ. Liu KG, et al. Bioorg Med Chem Lett. 2009 Jun 15;19(12):3214-6. doi: 10.1016/j.bmcl.2009.04.108. Epub 2009 May 3. Bioorg Med Chem Lett. 2009. PMID: 19433358

9

Development of an improved IP(1) assay for the characterization of 5-HT(2C) receptor ligands.

Zhang JY, Kowal DM, Nawoschik SP, Dunlop J, Pausch MH, Peri R. Zhang JY, et al. Assay Drug Dev Technol. 2010 Feb;8(1):106-13. doi: 10.1089/adt.2009.0205. Assay Drug Dev Technol. 2010. PMID: 19922239

10

Identification of 3-sulfonylindazole derivatives as potent and selective 5-HT(6) antagonists.

Liu KG, Robichaud AJ, Greenfield AA, Lo JR, Grosanu C, Mattes JF, Cai Y, Zhang GM, Zhang JY, Kowal DM, Smith DL, Di L, Kerns EH, Schechter LE, Comery TA. Liu KG, et al. Bioorg Med Chem. 2011 Jan 1;19(1):650-62. doi: 10.1016/j.bmc.2010.10.033. Epub 2010 Oct 20. Bioorg Med Chem. 2011. PMID: 21093272

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