Roller PP - Search Results

1

Structural basis for a non-phosphorus-containing cyclic peptide binding to Grb2-SH2 domain with high affinity.

Li P, Zhang M, Peach ML, Zhang X, Liu H, Nicklaus M, Yang D, Roller PP. Li P, et al. Among authors: roller pp. Biochem Biophys Res Commun. 2003 Aug 8;307(4):1038-44. doi: 10.1016/s0006-291x(03)01291-9. Biochem Biophys Res Commun. 2003. PMID: 12878216

2

Structure-based design of thioether-bridged cyclic phosphopeptides binding to Grb2-SH2 domain.

Li P, Peach ML, Zhang M, Liu H, Yang D, Nicklaus M, Roller PP. Li P, et al. Among authors: roller pp. Bioorg Med Chem Lett. 2003 Mar 10;13(5):895-9. doi: 10.1016/s0960-894x(03)00015-5. Bioorg Med Chem Lett. 2003. PMID: 12617916

3

Potent Grb2-SH2 domain antagonists not relying on phosphotyrosine mimics.

Li P, Zhang M, Long YQ, Peach ML, Liu H, Yang D, Nicklaus M, Roller PP. Li P, et al. Among authors: roller pp. Bioorg Med Chem Lett. 2003 Jul 7;13(13):2173-7. doi: 10.1016/s0960-894x(03)00385-8. Bioorg Med Chem Lett. 2003. PMID: 12798329

4

Concise and enantioselective synthesis of Fmoc-Pmp(But)2-OH and design of potent Pmp-containing Grb2-SH2 domain antagonists.

Li P, Zhang M, Peach ML, Liu H, Yang D, Roller PP. Li P, et al. Among authors: roller pp. Org Lett. 2003 Aug 21;5(17):3095-8. doi: 10.1021/ol035078+. Org Lett. 2003. PMID: 12916990

5

Potentiating effect of distant sites in non-phosphorylated cyclic peptide antagonists of the Grb2-SH2 domain.

Long YQ, Guo R, Luo JH, Yang D, Roller PP. Long YQ, et al. Among authors: roller pp. Biochem Biophys Res Commun. 2003 Oct 17;310(2):334-40. doi: 10.1016/j.bbrc.2003.09.022. Biochem Biophys Res Commun. 2003. PMID: 14521914

6

Structure-based design of potent Grb2-SH2 domain antagonists not relying on phosphotyrosine mimics.

Jiang S, Li P, Peach ML, Bindu L, Worthy KW, Fisher RJ, Burke TR Jr, Nicklaus M, Roller PP. Jiang S, et al. Among authors: roller pp. Biochem Biophys Res Commun. 2006 Oct 20;349(2):497-503. doi: 10.1016/j.bbrc.2006.08.059. Epub 2006 Aug 22. Biochem Biophys Res Commun. 2006. PMID: 16945340

7

Structural requirements for Tyr in the consensus sequence Y-E-N of a novel nonphosphorylated inhibitor to the Grb2-SH2 domain.

Long YQ, Yao ZJ, Voigt JH, Lung FD, Luo JH, Burke TR Jr, King CR, Yang D, Roller PP. Long YQ, et al. Among authors: roller pp. Biochem Biophys Res Commun. 1999 Nov 2;264(3):902-8. doi: 10.1006/bbrc.1999.1599. Biochem Biophys Res Commun. 1999. PMID: 10544028

8

Cyclization strategies in peptide derived drug design.

Li P, Roller PP. Li P, et al. Among authors: roller pp. Curr Top Med Chem. 2002 Mar;2(3):325-41. doi: 10.2174/1568026023394209. Curr Top Med Chem. 2002. PMID: 11944823 Review.

9

Small nonphosphorylated Grb2-SH2 domain antagonists evaluated by surface plasmon resonance technology.

Lung FD, Chang CW, Chong MC, Liou CC, Li P, Peach ML, Nicklaus MC, Lou BS, Roller PP. Lung FD, et al. Among authors: roller pp. Biopolymers. 2005;80(5):628-35. doi: 10.1002/bip.20209. Biopolymers. 2005. PMID: 15660381

10

Discovery of a novel nonphosphorylated pentapeptide motif displaying high affinity for Grb2-SH2 domain by the utilization of 3'-substituted tyrosine derivatives.

Song YL, Peach ML, Roller PP, Qiu S, Wang S, Long YQ. Song YL, et al. Among authors: roller pp. J Med Chem. 2006 Mar 9;49(5):1585-96. doi: 10.1021/jm050910x. J Med Chem. 2006. PMID: 16509576

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