Levy-Adam F - Search Results

1

Heterodimer formation is essential for heparanase enzymatic activity.

Levy-Adam F, Miao HQ, Heinrikson RL, Vlodavsky I, Ilan N. Levy-Adam F, et al. Biochem Biophys Res Commun. 2003 Sep 5;308(4):885-91. doi: 10.1016/s0006-291x(03)01478-5. Biochem Biophys Res Commun. 2003. PMID: 12927802

2

Processing and activation of latent heparanase occurs in lysosomes.

Zetser A, Levy-Adam F, Kaplan V, Gingis-Velitski S, Bashenko Y, Schubert S, Flugelman MY, Vlodavsky I, Ilan N. Zetser A, et al. J Cell Sci. 2004 May 1;117(Pt 11):2249-58. doi: 10.1242/jcs.01068. J Cell Sci. 2004. PMID: 15126626

3

Heparanase uptake is mediated by cell membrane heparan sulfate proteoglycans.

Gingis-Velitski S, Zetser A, Kaplan V, Ben-Zaken O, Cohen E, Levy-Adam F, Bashenko Y, Flugelman MY, Vlodavsky I, Ilan N. Gingis-Velitski S, et al. J Biol Chem. 2004 Oct 15;279(42):44084-92. doi: 10.1074/jbc.M402131200. Epub 2004 Jul 29. J Biol Chem. 2004. PMID: 15292202 Free article.

4

Identification and characterization of heparin/heparan sulfate binding domains of the endoglycosidase heparanase.

Levy-Adam F, Abboud-Jarrous G, Guerrini M, Beccati D, Vlodavsky I, Ilan N. Levy-Adam F, et al. J Biol Chem. 2005 May 27;280(21):20457-66. doi: 10.1074/jbc.M414546200. Epub 2005 Mar 10. J Biol Chem. 2005. PMID: 15760902 Free article.

5

Heparanase induces vascular endothelial growth factor expression: correlation with p38 phosphorylation levels and Src activation.

Zetser A, Bashenko Y, Edovitsky E, Levy-Adam F, Vlodavsky I, Ilan N. Zetser A, et al. Cancer Res. 2006 Feb 1;66(3):1455-63. doi: 10.1158/0008-5472.CAN-05-1811. Cancer Res. 2006. PMID: 16452201

6

Heparanase induces tissue factor pathway inhibitor expression and extracellular accumulation in endothelial and tumor cells.

Nadir Y, Brenner B, Gingis-Velitski S, Levy-Adam F, Ilan N, Zcharia E, Nadir E, Vlodavsky I. Nadir Y, et al. Thromb Haemost. 2008 Jan;99(1):133-41. Thromb Haemost. 2008. PMID: 18217145

7

Heparanase facilitates cell adhesion and spreading by clustering of cell surface heparan sulfate proteoglycans.

Levy-Adam F, Feld S, Suss-Toby E, Vlodavsky I, Ilan N. Levy-Adam F, et al. PLoS One. 2008 Jun 11;3(6):e2319. doi: 10.1371/journal.pone.0002319. PLoS One. 2008. PMID: 18545691 Free PMC article.

8

A novel human heparanase splice variant, T5, endowed with protumorigenic characteristics.

Barash U, Cohen-Kaplan V, Arvatz G, Gingis-Velitski S, Levy-Adam F, Nativ O, Shemesh R, Ayalon-Sofer M, Ilan N, Vlodavsky I. Barash U, et al. FASEB J. 2010 Apr;24(4):1239-48. doi: 10.1096/fj.09-147074. Epub 2009 Dec 9. FASEB J. 2010. PMID: 20007507 Free PMC article.

9

Heparanase 2 interacts with heparan sulfate with high affinity and inhibits heparanase activity.

Levy-Adam F, Feld S, Cohen-Kaplan V, Shteingauz A, Gross M, Arvatz G, Naroditsky I, Ilan N, Doweck I, Vlodavsky I. Levy-Adam F, et al. J Biol Chem. 2010 Sep 3;285(36):28010-9. doi: 10.1074/jbc.M110.116384. Epub 2010 Jun 24. J Biol Chem. 2010. PMID: 20576607 Free PMC article.

10

Tumorigenic and adhesive properties of heparanase.

Levy-Adam F, Ilan N, Vlodavsky I. Levy-Adam F, et al. Semin Cancer Biol. 2010 Jun;20(3):153-60. doi: 10.1016/j.semcancer.2010.06.005. Epub 2010 Jul 7. Semin Cancer Biol. 2010. PMID: 20619346 Free PMC article. Review.

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