Wang W - Search Results

1

Further SAR studies on novel small molecule inhibitors of the hepatitis C (HCV) NS5B polymerase.

Reddy TJ, Chan L, Turcotte N, Proulx M, Pereira OZ, Das SK, Siddiqui A, Wang W, Poisson C, Yannopoulos CG, Bilimoria D, L'Heureux L, Alaoui HM, Nguyen-Ba N. Reddy TJ, et al. Among authors: wang w. Bioorg Med Chem Lett. 2003 Oct 6;13(19):3341-4. doi: 10.1016/s0960-894x(03)00670-x. Bioorg Med Chem Lett. 2003. PMID: 12951122

2

Identification of N,N-disubstituted phenylalanines as a novel class of inhibitors of hepatitis C NS5B polymerase.

Chan L, Reddy TJ, Proulx M, Das SK, Pereira O, Wang W, Siddiqui A, Yannopoulos CG, Poisson C, Turcotte N, Drouin A, Alaoui-Ismaili MH, Bethell R, Hamel M, L'Heureux L, Bilimoria D, Nguyen-Ba N. Chan L, et al. Among authors: wang w. J Med Chem. 2003 Apr 10;46(8):1283-5. doi: 10.1021/jm0340400. J Med Chem. 2003. PMID: 12672227

3

Discovery of thiophene-2-carboxylic acids as potent inhibitors of HCV NS5B polymerase and HCV subgenomic RNA replication. Part 1: Sulfonamides.

Chan L, Das SK, Reddy TJ, Poisson C, Proulx M, Pereira O, Courchesne M, Roy C, Wang W, Siddiqui A, Yannopoulos CG, Nguyen-Ba N, Labrecque D, Bethell R, Hamel M, Courtemanche-Asselin P, L'Heureux L, David M, Nicolas O, Brunette S, Bilimoria D, Bédard J. Chan L, et al. Among authors: wang w. Bioorg Med Chem Lett. 2004 Feb 9;14(3):793-6. doi: 10.1016/j.bmcl.2003.10.067. Bioorg Med Chem Lett. 2004. PMID: 14741291

4

HCV NS5B polymerase-bound conformation of a soluble sulfonamide inhibitor by 2D transferred NOESY.

Yannopoulos CG, Xu P, Ni F, Chan L, Pereira OZ, Reddy TJ, Das SK, Poisson C, Nguyen-Ba N, Turcotte N, Proulx M, Halab L, Wang W, Bédard J, Morin N, Hamel M, Nicolas O, Bilimoria D, L'Heureux L, Bethell R, Dionne G. Yannopoulos CG, et al. Among authors: wang w. Bioorg Med Chem Lett. 2004 Nov 1;14(21):5333-7. doi: 10.1016/j.bmcl.2004.08.018. Bioorg Med Chem Lett. 2004. PMID: 15454222

5

Discovery of 1,6-naphthyridines as a novel class of potent and selective human cytomegalovirus inhibitors.

Chan L, Jin H, Stefanac T, Lavallée JF, Falardeau G, Wang W, Bédard J, May S, Yuen L. Chan L, et al. Among authors: wang w. J Med Chem. 1999 Aug 12;42(16):3023-5. doi: 10.1021/jm9902483. J Med Chem. 1999. PMID: 10447945 No abstract available.

6

Isoquinoline-6-carboxamides as potent and selective anti-human cytomegalovirus (HCMV) inhibitors.

Chan L, Jin H, Stefanac T, Wang W, Lavallée JF, Bédard J, May S. Chan L, et al. Among authors: wang w. Bioorg Med Chem Lett. 1999 Sep 6;9(17):2583-6. doi: 10.1016/s0960-894x(99)00435-7. Bioorg Med Chem Lett. 1999. PMID: 10498213

7

Hepatitis C viral IRES inhibition by phenazine and phenazine-like molecules.

Wang W, Préville P, Morin N, Mounir S, Cai W, Siddiqui MA. Wang W, et al. Bioorg Med Chem Lett. 2000 Jun 5;10(11):1151-4. doi: 10.1016/s0960-894x(00)00217-1. Bioorg Med Chem Lett. 2000. PMID: 10866369

8

Novel 1,3-disubstituted-5,10-dihydro-5,10-dioxo-1H-benzo[g] isochromene-3 carboxamides as potent antitumor agents.

Wang W, Li T, Milburn R, Yates J, Hinnant E, Luzzio MJ, Noble SA, Attardo G. Wang W, et al. Bioorg Med Chem Lett. 1998 Jul 7;8(13):1579-84. doi: 10.1016/s0960-894x(98)00274-1. Bioorg Med Chem Lett. 1998. PMID: 9873394

9

Synthesis and structure-activity relationships of a series of novel thiazoles as inhibitors of aminoacyl-tRNA synthetases.

Yu XY, Hill JM, Yu G, Wang W, Kluge AF, Wendler P, Gallant P. Yu XY, et al. Among authors: wang w. Bioorg Med Chem Lett. 1999 Feb 8;9(3):375-80. doi: 10.1016/s0960-894x(98)00738-0. Bioorg Med Chem Lett. 1999. PMID: 10091687

10

Design and synthesis of monocyclic beta-lactams as mechanism-based inhibitors of human cytomegalovirus protease.

Borthwick AD, Weingarten G, Haley TM, Tomaszewski M, Wang W, Hu Z, Bedard J, Jin H, Yuen L, Mansour TS. Borthwick AD, et al. Among authors: wang w. Bioorg Med Chem Lett. 1998 Feb 17;8(4):365-70. doi: 10.1016/s0960-894x(98)00032-8. Bioorg Med Chem Lett. 1998. PMID: 9871686

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