Tomizawa H - Search Results

1

Synthesis and evaluation of 6-nitro-7-(1-piperazino)quinazolines: dual-acting compounds with inhibitory activities toward both tumor necrosis factor-alpha (TNF-alpha) production and T cell proliferation.

Tobe M, Isobe Y, Tomizawa H, Nagasaki T, Aoki M, Negishi T, Hayashi H. Tobe M, et al. Among authors: tomizawa h. Chem Pharm Bull (Tokyo). 2003 Sep;51(9):1109-12. doi: 10.1248/cpb.51.1109. Chem Pharm Bull (Tokyo). 2003. PMID: 12951460 Free article.

2

Structure-activity relationships of 6-nitroquinazolines: dual-acting compounds with inhibitory activities toward both TNF-alpha production and T cell proliferation.

Tobe M, Isobe Y, Tomizawa H, Nagasaki T, Obara F, Matsumoto M, Hayashi H. Tobe M, et al. Among authors: tomizawa h. Chem Pharm Bull (Tokyo). 2002 Aug;50(8):1073-80. doi: 10.1248/cpb.50.1073. Chem Pharm Bull (Tokyo). 2002. PMID: 12192139 Free article.

3

Discovery of quinazolines as a novel structural class of potent inhibitors of NF-kappa B activation.

Tobe M, Isobe Y, Tomizawa H, Nagasaki T, Takahashi H, Fukazawa T, Hayashi H. Tobe M, et al. Among authors: tomizawa h. Bioorg Med Chem. 2003 Feb 6;11(3):383-91. doi: 10.1016/s0968-0896(02)00440-6. Bioorg Med Chem. 2003. PMID: 12517433

4

Structure-activity relationships of 6-fluoroquinazolines: dual-acting compounds with inhibitory activities toward both TNF-alpha production and T cell proliferation.

Tobe M, Isobe Y, Tomizawa H, Nagasaki T, Obara F, Hayashi H. Tobe M, et al. Among authors: tomizawa h. Bioorg Med Chem. 2003 Feb 20;11(4):609-16. doi: 10.1016/s0968-0896(02)00338-3. Bioorg Med Chem. 2003. PMID: 12538026

5

Structure-activity relationships of quinazoline derivatives: dual-acting compounds with inhibitory activities toward both TNF-alpha production and T cell proliferation.

Tobe M, Isobe Y, Tomizawa H, Matsumoto M, Obara F, Nagasaki T, Hayashi H. Tobe M, et al. Among authors: tomizawa h. Bioorg Med Chem Lett. 2001 Feb 26;11(4):545-8. doi: 10.1016/s0960-894x(00)00718-6. Bioorg Med Chem Lett. 2001. PMID: 11229767

6

A novel structural class of potent inhibitors of NF-kappa B activation: structure-activity relationships and biological effects of 6-aminoquinazoline derivatives.

Tobe M, Isobe Y, Tomizawa H, Nagasaki T, Takahashi H, Hayashi H. Tobe M, et al. Among authors: tomizawa h. Bioorg Med Chem. 2003 Sep 1;11(18):3869-78. doi: 10.1016/s0968-0896(03)00438-3. Bioorg Med Chem. 2003. PMID: 12927847

7

Dihydropyrrolo[2,3-d]pyrimidines: Selective Toll-Like Receptor 9 Antagonists from Scaffold Morphing Efforts.

Watanabe M, Kasai M, Tomizawa H, Aoki M, Eiho K, Isobe Y, Asano S. Watanabe M, et al. Among authors: tomizawa h. ACS Med Chem Lett. 2014 Oct 2;5(11):1235-9. doi: 10.1021/ml5003184. eCollection 2014 Nov 13. ACS Med Chem Lett. 2014. PMID: 25408837 Free PMC article.

8

Intratracheal and oral administration of SM-276001: a selective TLR7 agonist, leads to antitumor efficacy in primary and metastatic models of cancer.

Koga-Yamakawa E, Dovedi SJ, Murata M, Matsui H, Leishman AJ, Bell J, Ferguson D, Heaton SP, Oki T, Tomizawa H, Bahl A, Takaku H, Wilkinson RW, Harada H. Koga-Yamakawa E, et al. Among authors: tomizawa h. Int J Cancer. 2013 Feb 1;132(3):580-90. doi: 10.1002/ijc.27691. Epub 2012 Jul 11. Int J Cancer. 2013. PMID: 22733292

9

Biological characterization of a novel class of toll-like receptor 7 agonists designed to have reduced systemic activity.

Biffen M, Matsui H, Edwards S, Leishman AJ, Eiho K, Holness E, Satterthwaite G, Doyle I, Wada H, Fraser NJ, Hawkins SL, Aoki M, Tomizawa H, Benjamin AD, Takaku H, McInally T, Murray CM. Biffen M, et al. Among authors: tomizawa h. Br J Pharmacol. 2012 May;166(2):573-86. doi: 10.1111/j.1476-5381.2011.01790.x. Br J Pharmacol. 2012. PMID: 22122192 Free PMC article.

10

Molecular cloning and chromosomal mapping of a bone marrow stromal cell surface gene, BST2, that may be involved in pre-B-cell growth.

Ishikawa J, Kaisho T, Tomizawa H, Lee BO, Kobune Y, Inazawa J, Oritani K, Itoh M, Ochi T, Ishihara K, et al. Ishikawa J, et al. Among authors: tomizawa h. Genomics. 1995 Apr 10;26(3):527-34. doi: 10.1016/0888-7543(95)80171-h. Genomics. 1995. PMID: 7607676

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