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High basal protein kinase A-dependent phosphorylation drives rhythmic internal Ca2+ store oscillations and spontaneous beating of cardiac pacemaker cells.
Vinogradova TM, Lyashkov AE, Zhu W, Ruknudin AM, Sirenko S, Yang D, Deo S, Barlow M, Johnson S, Caffrey JL, Zhou YY, Xiao RP, Cheng H, Stern MD, Maltsev VA, Lakatta EG. Vinogradova TM, et al. Among authors: zhu w. Circ Res. 2006 Mar 3;98(4):505-14. doi: 10.1161/01.RES.0000204575.94040.d1. Epub 2006 Jan 19. Circ Res. 2006. PMID: 16424365
RGS2 is a primary terminator of β₂-adrenergic receptor-mediated G(i) signaling.
Chakir K, Zhu W, Tsang S, Woo AY, Yang D, Wang X, Zeng X, Rhee MH, Mende U, Koitabashi N, Takimoto E, Blumer KJ, Lakatta EG, Kass DA, Xiao RP. Chakir K, et al. Among authors: zhu w. J Mol Cell Cardiol. 2011 Jun;50(6):1000-7. doi: 10.1016/j.yjmcc.2011.01.015. Epub 2011 Feb 1. J Mol Cell Cardiol. 2011. PMID: 21291891 Free PMC article.
Gi-biased β2AR signaling links GRK2 upregulation to heart failure.
Zhu W, Petrashevskaya N, Ren S, Zhao A, Chakir K, Gao E, Chuprun JK, Wang Y, Talan M, Dorn GW 2nd, Lakatta EG, Koch WJ, Feldman AM, Xiao RP. Zhu W, et al. Circ Res. 2012 Jan 20;110(2):265-74. doi: 10.1161/CIRCRESAHA.111.253260. Epub 2011 Dec 15. Circ Res. 2012. PMID: 22179058 Free PMC article.
Mechanisms of enhanced beta-adrenergic reserve from cardiac resynchronization therapy.
Chakir K, Daya SK, Aiba T, Tunin RS, Dimaano VL, Abraham TP, Jaques-Robinson KM, Lai EW, Pacak K, Zhu WZ, Xiao RP, Tomaselli GF, Kass DA. Chakir K, et al. Among authors: zhu wz. Circulation. 2009 Mar 10;119(9):1231-40. doi: 10.1161/CIRCULATIONAHA.108.774752. Epub 2009 Feb 23. Circulation. 2009. PMID: 19237665 Free PMC article.
19,165 results
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