Besmer P - Search Results

1

Allelic deletions in the long arm of chromosome 12 identify sites of candidate tumor suppressor genes in male germ cell tumors.

Murty VV, Houldsworth J, Baldwin S, Reuter V, Hunziker W, Besmer P, Bosl G, Chaganti RS. Murty VV, et al. Among authors: besmer p. Proc Natl Acad Sci U S A. 1992 Nov 15;89(22):11006-10. doi: 10.1073/pnas.89.22.11006. Proc Natl Acad Sci U S A. 1992. PMID: 1332066 Free PMC article.

2

The Wsh and Ph mutations affect the c-kit expression profile: c-kit misexpression in embryogenesis impairs melanogenesis in Wsh and Ph mutant mice.

Duttlinger R, Manova K, Berrozpe G, Chu TY, DeLeon V, Timokhina I, Chaganti RS, Zelenetz AD, Bachvarova RF, Besmer P. Duttlinger R, et al. Among authors: besmer p. Proc Natl Acad Sci U S A. 1995 Apr 25;92(9):3754-8. doi: 10.1073/pnas.92.9.3754. Proc Natl Acad Sci U S A. 1995. PMID: 7537375 Free PMC article.

3

Oncogenic Kit signaling and therapeutic intervention in a mouse model of gastrointestinal stromal tumor.

Rossi F, Ehlers I, Agosti V, Socci ND, Viale A, Sommer G, Yozgat Y, Manova K, Antonescu CR, Besmer P. Rossi F, et al. Among authors: besmer p. Proc Natl Acad Sci U S A. 2006 Aug 22;103(34):12843-8. doi: 10.1073/pnas.0511076103. Epub 2006 Aug 14. Proc Natl Acad Sci U S A. 2006. PMID: 16908864 Free PMC article.

4

Gastrointestinal stromal tumors in a mouse model by targeted mutation of the Kit receptor tyrosine kinase.

Sommer G, Agosti V, Ehlers I, Rossi F, Corbacioglu S, Farkas J, Moore M, Manova K, Antonescu CR, Besmer P. Sommer G, et al. Among authors: besmer p. Proc Natl Acad Sci U S A. 2003 May 27;100(11):6706-11. doi: 10.1073/pnas.1037763100. Epub 2003 May 16. Proc Natl Acad Sci U S A. 2003. PMID: 12754375 Free PMC article.

5

Consequences of exclusive expression in vivo of Kit-ligand lacking the major proteolytic cleavage site.

Tajima Y, Moore MA, Soares V, Ono M, Kissel H, Besmer P. Tajima Y, et al. Among authors: besmer p. Proc Natl Acad Sci U S A. 1998 Sep 29;95(20):11903-8. doi: 10.1073/pnas.95.20.11903. Proc Natl Acad Sci U S A. 1998. PMID: 9751763 Free PMC article.

6

High-frequency cotransfer of the transformed phenotype and a tumor-specific transplantation antigen by DNA from the 3-methylcholanthrene-induced Meth A sarcoma of BALB/c mice.

Hopkins N, Besmer P, DeLeo AB, Law LW. Hopkins N, et al. Among authors: besmer p. Proc Natl Acad Sci U S A. 1981 Dec;78(12):7555-9. doi: 10.1073/pnas.78.12.7555. Proc Natl Acad Sci U S A. 1981. PMID: 6950396 Free PMC article.

7

Imatinib resistance and microcytic erythrocytosis in a KitV558Δ;T669I/+ gatekeeper-mutant mouse model of gastrointestinal stromal tumor.

Bosbach B, Deshpande S, Rossi F, Shieh JH, Sommer G, de Stanchina E, Veach DR, Scandura JM, Manova-Todorova K, Moore MA, Antonescu CR, Besmer P. Bosbach B, et al. Among authors: besmer p. Proc Natl Acad Sci U S A. 2012 Aug 21;109(34):E2276-83. doi: 10.1073/pnas.1115240109. Epub 2012 May 31. Proc Natl Acad Sci U S A. 2012. PMID: 22652566 Free PMC article.

8

Direct engagement of the PI3K pathway by mutant KIT dominates oncogenic signaling in gastrointestinal stromal tumor.

Bosbach B, Rossi F, Yozgat Y, Loo J, Zhang JQ, Berrozpe G, Warpinski K, Ehlers I, Veach D, Kwok A, Manova K, Antonescu CR, DeMatteo RP, Besmer P. Bosbach B, et al. Among authors: besmer p. Proc Natl Acad Sci U S A. 2017 Oct 3;114(40):E8448-E8457. doi: 10.1073/pnas.1711449114. Epub 2017 Sep 18. Proc Natl Acad Sci U S A. 2017. PMID: 28923937 Free PMC article.

9

Molecular bases of dominant negative and loss of function mutations at the murine c-kit/white spotting locus: W37, Wv, W41 and W.

Nocka K, Tan JC, Chiu E, Chu TY, Ray P, Traktman P, Besmer P. Nocka K, et al. Among authors: besmer p. EMBO J. 1990 Jun;9(6):1805-13. doi: 10.1002/j.1460-2075.1990.tb08305.x. EMBO J. 1990. PMID: 1693331 Free PMC article.

10

The hematopoietic growth factor KL is encoded by the Sl locus and is the ligand of the c-kit receptor, the gene product of the W locus.

Huang E, Nocka K, Beier DR, Chu TY, Buck J, Lahm HW, Wellner D, Leder P, Besmer P. Huang E, et al. Among authors: besmer p. Cell. 1990 Oct 5;63(1):225-33. doi: 10.1016/0092-8674(90)90303-v. Cell. 1990. PMID: 1698557 Free article.

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