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Mice expressing a humanized form of VEGF-A may provide insights into the safety and efficacy of anti-VEGF antibodies.
Gerber HP, Wu X, Yu L, Wiesmann C, Liang XH, Lee CV, Fuh G, Olsson C, Damico L, Xie D, Meng YG, Gutierrez J, Corpuz R, Li B, Hall L, Rangell L, Ferrando R, Lowman H, Peale F, Ferrara N. Gerber HP, et al. Among authors: li b. Proc Natl Acad Sci U S A. 2007 Feb 27;104(9):3478-83. doi: 10.1073/pnas.0611492104. Epub 2007 Feb 20. Proc Natl Acad Sci U S A. 2007. PMID: 17360669 Free PMC article.
Development and preclinical characterization of a humanized antibody targeting CXCL12.
Zhong C, Wang J, Li B, Xiang H, Ultsch M, Coons M, Wong T, Chiang NY, Clark S, Clark R, Quintana L, Gribling P, Suto E, Barck K, Corpuz R, Yao J, Takkar R, Lee WP, Damico-Beyer LA, Carano RD, Adams C, Kelley RF, Wang W, Ferrara N. Zhong C, et al. Among authors: li b. Clin Cancer Res. 2013 Aug 15;19(16):4433-45. doi: 10.1158/1078-0432.CCR-13-0943. Epub 2013 Jun 28. Clin Cancer Res. 2013. PMID: 23812669
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