Howells RE - Search Results

1

Rapid chloroquine efflux phenotype in both chloroquine-sensitive and chloroquine-resistant Plasmodium falciparum. A correlation of chloroquine sensitivity with energy-dependent drug accumulation.

Bray PG, Howells RE, Ritchie GY, Ward SA. Bray PG, et al. Among authors: howells re. Biochem Pharmacol. 1992 Oct 6;44(7):1317-24. doi: 10.1016/0006-2952(92)90532-n. Biochem Pharmacol. 1992. PMID: 1417955

2

Relationship of global chloroquine transport and reversal of resistance in Plasmodium falciparum.

Bray PG, Boulter MK, Ritchie GY, Howells RE, Ward SA. Bray PG, et al. Among authors: howells re. Mol Biochem Parasitol. 1994 Jan;63(1):87-94. doi: 10.1016/0166-6851(94)90011-6. Mol Biochem Parasitol. 1994. PMID: 8183326

3

The potential of desipramine to reverse chloroquine resistance of Plasmodium falciparum is reduced by its binding to plasma protein.

Boulter MK, Bray PG, Howells RE, Ward SA. Boulter MK, et al. Among authors: howells re. Trans R Soc Trop Med Hyg. 1993 May-Jun;87(3):303. doi: 10.1016/0035-9203(93)90137-f. Trans R Soc Trop Med Hyg. 1993. PMID: 8236399 No abstract available.

4

Development of halofantrine resistance and determination of cross-resistance patterns in Plasmodium falciparum.

Nateghpour M, Ward SA, Howells RE. Nateghpour M, et al. Among authors: howells re. Antimicrob Agents Chemother. 1993 Nov;37(11):2337-43. doi: 10.1128/AAC.37.11.2337. Antimicrob Agents Chemother. 1993. PMID: 8285616 Free PMC article.

5

Enhancement of drug susceptibility in Plasmodium falciparum in vitro and Plasmodium berghei in vivo by mixed-function oxidase inhibitors.

Ndifor AM, Howells RE, Bray PG, Ngu JL, Ward SA. Ndifor AM, et al. Among authors: howells re. Antimicrob Agents Chemother. 1993 Jun;37(6):1318-23. doi: 10.1128/AAC.37.6.1318. Antimicrob Agents Chemother. 1993. PMID: 8328780 Free PMC article.

6

Chloroquine sensitivity of Plasmodium falciparum in vivo in a savanna town in Cameroon.

Ndifor AM, Howells RE, Ward SA. Ndifor AM, et al. Among authors: howells re. Trans R Soc Trop Med Hyg. 1992 May-Jun;86(3):229-30. doi: 10.1016/0035-9203(92)90284-j. Trans R Soc Trop Med Hyg. 1992. PMID: 1412637

7

Vacuolar acidification and chloroquine sensitivity in Plasmodium falciparum.

Bray PG, Howells RE, Ward SA. Bray PG, et al. Among authors: howells re. Biochem Pharmacol. 1992 Mar 17;43(6):1219-27. doi: 10.1016/0006-2952(92)90495-5. Biochem Pharmacol. 1992. PMID: 1562274

8

Cytochrome P-450 activity in malarial parasites and its possible relationship to chloroquine resistance.

Ndifor AM, Ward SA, Howells RE. Ndifor AM, et al. Among authors: howells re. Mol Biochem Parasitol. 1990 Jun;41(2):251-7. doi: 10.1016/0166-6851(90)90188-r. Mol Biochem Parasitol. 1990. PMID: 2204831

9

In vitro metabolism of the biguanide antimalarials in human liver microsomes: evidence for a role of the mephenytoin hydroxylase (P450 MP) enzyme.

Helsby NA, Ward SA, Howells RE, Breckenridge AM. Helsby NA, et al. Among authors: howells re. Br J Clin Pharmacol. 1990 Aug;30(2):287-91. doi: 10.1111/j.1365-2125.1990.tb03777.x. Br J Clin Pharmacol. 1990. PMID: 2206791 Free PMC article.

10

The pharmacokinetics and activation of proguanil in man: consequences of variability in drug metabolism.

Helsby NA, Ward SA, Edwards G, Howells RE, Breckenridge AM. Helsby NA, et al. Among authors: howells re. Br J Clin Pharmacol. 1990 Oct;30(4):593-8. doi: 10.1111/j.1365-2125.1990.tb03818.x. Br J Clin Pharmacol. 1990. PMID: 2291871 Free PMC article.

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