Le Monnier de Gouville AC - Search Results

1

The discovery of tadalafil: a novel and highly selective PDE5 inhibitor. 2: 2,3,6,7,12,12a-hexahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione analogues.

Daugan A, Grondin P, Ruault C, Le Monnier de Gouville AC, Coste H, Linget JM, Kirilovsky J, Hyafil F, Labaudinière R. Daugan A, et al. Among authors: le monnier de gouville ac. J Med Chem. 2003 Oct 9;46(21):4533-42. doi: 10.1021/jm0300577. J Med Chem. 2003. PMID: 14521415

2

The discovery of tadalafil: a novel and highly selective PDE5 inhibitor. 1: 5,6,11,11a-tetrahydro-1H-imidazo[1',5':1,6]pyrido[3,4-b]indole-1,3(2H)-dione analogues.

Daugan A, Grondin P, Ruault C, Le Monnier de Gouville AC, Coste H, Kirilovsky J, Hyafil F, Labaudinière R. Daugan A, et al. Among authors: le monnier de gouville ac. J Med Chem. 2003 Oct 9;46(21):4525-32. doi: 10.1021/jm030056e. J Med Chem. 2003. PMID: 14521414

3

Cardiovascular effects of a novel, potent and selective phosphodiesterase 5 inhibitor, DMPPO: in vitro and in vivo characterization.

Delpy E, le Monnier de Gouville AC. Delpy E, et al. Among authors: le monnier de gouville ac. Br J Pharmacol. 1996 Jul;118(6):1377-84. doi: 10.1111/j.1476-5381.1996.tb15548.x. Br J Pharmacol. 1996. PMID: 8832060 Free PMC article.

4

Effect of DMPPO, a phosphodiesterase type 5 inhibitor, on hypoxic pulmonary hypertension in rats.

Eddahibi S, Raffestin B, Le Monnier de Gouville AC, Adnot S. Eddahibi S, et al. Among authors: le monnier de gouville ac. Br J Pharmacol. 1998 Oct;125(4):681-8. doi: 10.1038/sj.bjp.0702124. Br J Pharmacol. 1998. PMID: 9831902 Free PMC article.

5

Cross tachyphylaxis to endothelin isopeptide-induced hypotension: a phenomenon not seen with proendothelin.

Le Monnier de Gouville AC, Cavero I. Le Monnier de Gouville AC, et al. Br J Pharmacol. 1991 Sep;104(1):77-84. doi: 10.1111/j.1476-5381.1991.tb12388.x. Br J Pharmacol. 1991. PMID: 1786522 Free PMC article.

6

Hemodynamic and pharmacological evaluation of the vasodilator and vasoconstrictor effects of endothelin-1 in rats.

Le Monnier de Gouville AC, Mondot S, Lippton H, Hyman A, Cavero I. Le Monnier de Gouville AC, et al. J Pharmacol Exp Ther. 1990 Jan;252(1):300-11. J Pharmacol Exp Ther. 1990. PMID: 2405151

7

SK&F 87516, a close analog of fenoldopam, is a partial agonist at dopamine-1 and alpha-2 receptors and produces stimulation of 5-hydroxytryptamine-2 receptors in the cardiovascular system of the rat.

Le Monnier de Gouville AC, Lawson K, Thiry C, Cavero I. Le Monnier de Gouville AC, et al. J Pharmacol Exp Ther. 1991 Mar;256(3):1049-56. J Pharmacol Exp Ther. 1991. PMID: 1672375

8

Differential inhibition of the pressor effects of natural pro-endothelins by phosphoramidon in rats.

Le Monnier de Gouville AC, Thiry C, Cavero I. Le Monnier de Gouville AC, et al. Fundam Clin Pharmacol. 1994;8(4):342-6. doi: 10.1111/j.1472-8206.1994.tb00811.x. Fundam Clin Pharmacol. 1994. PMID: 7851839

9

GSK256073 acutely regulates NEFA levels via HCA2 agonism but does not achieve durable glycaemic control in type 2 diabetes. A randomised trial.

Dobbins R, Byerly R, Gaddy R, Gao F, Mahar K, Napolitano A, Ambery P, Le Monnier de Gouville AC. Dobbins R, et al. Among authors: le monnier de gouville ac. Eur J Pharmacol. 2015 May 15;755:95-101. doi: 10.1016/j.ejphar.2015.03.005. Epub 2015 Mar 13. Eur J Pharmacol. 2015. PMID: 25773496 Clinical Trial.

10

Differential pharmacological profile of endothelin-1 and its precursor, big endothelin.

Le Monnier de Gouville AC, Cavero I. Le Monnier de Gouville AC, et al. J Cardiovasc Pharmacol. 1991;17 Suppl 7:S362-5. doi: 10.1097/00005344-199100177-00103. J Cardiovasc Pharmacol. 1991. PMID: 1725381

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