Shim HJ - Search Results

1

Sensitive liquid chromatography assay with ultraviolet detection for a new phosphodiesterase V inhibitor, DA-8159, in human plasma and urine.

Cho JY, Lim HS, Yu KS, Shim HJ, Jang IJ, Shin SG. Cho JY, et al. Among authors: shim hj. J Chromatogr B Analyt Technol Biomed Life Sci. 2003 Oct 5;795(2):179-86. doi: 10.1016/s1570-0232(03)00565-8. J Chromatogr B Analyt Technol Biomed Life Sci. 2003. PMID: 14522022

2

Determination of a new phosphodiesterase V inhibitor, DA-8159, in plasma and urine by high-performance liquid chromatography.

Shim HJ, Lee EJ, Jung YH, Kim SH, Kim SH, Yoo M, Kwon JW, Kim WB, Lee MG. Shim HJ, et al. J Pharm Biomed Anal. 2002 Oct 15;30(3):527-33. doi: 10.1016/s0731-7085(02)00397-7. J Pharm Biomed Anal. 2002. PMID: 12367677

3

Subacute toxicities and toxicokinetics of DA-8159, a new phosphodiesterase type V inhibitor, after single and 4-week repeated oral administration in rats.

Shim HJ, Kim YC, Jang JM, Park KJ, Kim DH, Kang KK, Ahn BO, Kwon JW, Kim WB, Lee MG. Shim HJ, et al. Biopharm Drug Dispos. 2003 Dec;24(9):409-18. doi: 10.1002/bdd.377. Biopharm Drug Dispos. 2003. PMID: 14689469

4

DA-8159 has erectile potentials much longer than the plasma half-life in a conscious rabbit model.

Kang KK, Ahn GJ, Shim HJ, Kwon JW. Kang KK, et al. Among authors: shim hj. Life Sci. 2004 Jul 16;75(9):1075-83. doi: 10.1016/j.lfs.2004.02.017. Life Sci. 2004. PMID: 15207655

5

Pharmacokinetic changes of DA-8159, a new erectogenic, after intravenous and oral administration to rats with acute renal failure induced by uranyl nitrate.

Shim HJ, Kim YC, Kim EJ, Kim DG, Kwon JW, Kim WB, Lee MG. Shim HJ, et al. Biopharm Drug Dispos. 2004 Apr;25(3):137-42. doi: 10.1002/bdd.389. Biopharm Drug Dispos. 2004. PMID: 15083502

6

Effect of DA-8159, a selective phosphodiesterase type 5 inhibitor, on electroretinogram and retinal histology in rabbits.

Cho HK, Kang KK, Ahn GJ, Shim HJ, Kim WB. Cho HK, et al. Among authors: shim hj. J Korean Med Sci. 2004 Aug;19(4):586-90. doi: 10.3346/jkms.2004.19.4.586. J Korean Med Sci. 2004. PMID: 15308852 Free PMC article.

7

Species differences in the formation of DA-8164 after intravenous and/or oral administration of DA-8159, a new erectogenic, to mice, rats, rabbits, dogs and humans.

Shim HJ, Kim YC, Lee JH, Park KJ, Kwon JW, Kim WB, Lee MG. Shim HJ, et al. Biopharm Drug Dispos. 2005 May;26(4):161-6. doi: 10.1002/bdd.444. Biopharm Drug Dispos. 2005. PMID: 15803515

8

Pharmacokinetics of DA-8159, a new erectogenic, after intravenous and oral administration to rats: hepatic and intestinal first-pass effects.

Shim HJ, Kim YC, Park KJ, Kim DS, Kwon JW, Kim WB, Lee MG. Shim HJ, et al. J Pharm Sci. 2003 Nov;92(11):2185-95. doi: 10.1002/jps.10482. J Pharm Sci. 2003. PMID: 14603504

9

Quantification of a novel PPARγ partial agonist (S)-2-ethoxy-3-(4-{3-methyl-5-[4-(3-methyl-isoxazol-5-yl)-phenyl]thiophen-2-ylmethoxy}-phenyl)-propionic acid (PAM-1616) in rat plasma using liquid chromatography-tandem mass spectrometry.

Chae HW, Jung H, Kim EJ, Shim HJ, Lim JI, Ji HY, Lee HS. Chae HW, et al. Among authors: shim hj. Arch Pharm Res. 2010 Sep;33(9):1389-94. doi: 10.1007/s12272-010-0912-z. Epub 2010 Oct 9. Arch Pharm Res. 2010. PMID: 20945137

10

Pharmacokinetic changes of DA-8159, a new erectogenic, and one of its metabolites, DA-8164 after intravenous and oral administration of DA-8159 to spontaneously hypertensive rats and DOCA-salt-induced hypertensive rats.

Kim YC, Shim HJ, Lee JH, Kim DS, Kwon JW, Kim WB, Lee I, Lee MG. Kim YC, et al. Among authors: shim hj. Biopharm Drug Dispos. 2005 Oct;26(7):309-20. doi: 10.1002/bdd.462. Biopharm Drug Dispos. 2005. PMID: 16035131

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