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PS2APP transgenic mice, coexpressing hPS2mut and hAPPswe, show age-related cognitive deficits associated with discrete brain amyloid deposition and inflammation.
Richards JG, Higgins GA, Ouagazzal AM, Ozmen L, Kew JN, Bohrmann B, Malherbe P, Brockhaus M, Loetscher H, Czech C, Huber G, Bluethmann H, Jacobsen H, Kemp JA. Richards JG, et al. Among authors: czech c. J Neurosci. 2003 Oct 1;23(26):8989-9003. doi: 10.1523/JNEUROSCI.23-26-08989.2003. J Neurosci. 2003. PMID: 14523101 Free PMC article.
Amyloid-beta and tau synergistically impair the oxidative phosphorylation system in triple transgenic Alzheimer's disease mice.
Rhein V, Song X, Wiesner A, Ittner LM, Baysang G, Meier F, Ozmen L, Bluethmann H, Dröse S, Brandt U, Savaskan E, Czech C, Götz J, Eckert A. Rhein V, et al. Among authors: czech c. Proc Natl Acad Sci U S A. 2009 Nov 24;106(47):20057-62. doi: 10.1073/pnas.0905529106. Epub 2009 Nov 6. Proc Natl Acad Sci U S A. 2009. PMID: 19897719 Free PMC article.
Novel orally active, dibenzazepinone-based gamma-secretase inhibitors.
Peters JU, Galley G, Jacobsen H, Czech C, David-Pierson P, Kitas EA, Ozmen L. Peters JU, et al. Among authors: czech c. Bioorg Med Chem Lett. 2007 Nov 1;17(21):5918-23. doi: 10.1016/j.bmcl.2007.07.078. Epub 2007 Aug 22. Bioorg Med Chem Lett. 2007. PMID: 17869099
Striatum and entorhinal cortex atrophy in AD mouse models: MRI comprehensive analysis.
Micotti E, Paladini A, Balducci C, Tolomeo D, Frasca A, Marizzoni M, Filibian M, Caroli A, Valbusa G, Dix S, O'Neill M, Ozmen L, Czech C, Richardson JC, Frisoni GB, Forloni G. Micotti E, et al. Among authors: czech c. Neurobiol Aging. 2015 Feb;36(2):776-88. doi: 10.1016/j.neurobiolaging.2014.10.027. Epub 2014 Oct 25. Neurobiol Aging. 2015. PMID: 25433456
A 13 kDa carboxy-terminal fragment of ApoE stabilizes Abeta hexamers.
Wellnitz S, Friedlein A, Bonanni C, Anquez V, Goepfert F, Loetscher H, Adessi C, Czech C. Wellnitz S, et al. Among authors: czech c. J Neurochem. 2005 Sep;94(5):1351-60. doi: 10.1111/j.1471-4159.2005.03295.x. Epub 2005 Jul 11. J Neurochem. 2005. PMID: 16011742 Free article.
115 results