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Identification of the human cytochrome P450, P450RAI-2, which is predominantly expressed in the adult cerebellum and is responsible for all-trans-retinoic acid metabolism.
White JA, Ramshaw H, Taimi M, Stangle W, Zhang A, Everingham S, Creighton S, Tam SP, Jones G, Petkovich M. White JA, et al. Among authors: petkovich m. Proc Natl Acad Sci U S A. 2000 Jun 6;97(12):6403-8. doi: 10.1073/pnas.120161397. Proc Natl Acad Sci U S A. 2000. PMID: 10823918 Free PMC article.
cDNA cloning of human retinoic acid-metabolizing enzyme (hP450RAI) identifies a novel family of cytochromes P450.
White JA, Beckett-Jones B, Guo YD, Dilworth FJ, Bonasoro J, Jones G, Petkovich M. White JA, et al. Among authors: petkovich m. J Biol Chem. 1997 Jul 25;272(30):18538-41. doi: 10.1074/jbc.272.30.18538. J Biol Chem. 1997. PMID: 9228017 Free article.
Res. 50, 317-32; Mangelsdorf, D. J., and Evans, R. M. (1995) Cell 83, 841-850; Petkovich, M. (1992) Annu. Rev. Nutr. 12, 443-471). Evidence suggests that 4-hydroxylation of RA inside the target cell limits its biological activity and initiates a degradative p …
Res. 50, 317-32; Mangelsdorf, D. J., and Evans, R. M. (1995) Cell 83, 841-850; Petkovich, M. (1992) Annu. Rev. Nutr. 12 …
Regulation of retinoic acid metabolism.
Luu L, Ramshaw H, Tahayato A, Stuart A, Jones G, White J, Petkovich M. Luu L, et al. Among authors: petkovich m. Adv Enzyme Regul. 2001;41:159-75. doi: 10.1016/s0065-2571(00)00024-8. Adv Enzyme Regul. 2001. PMID: 11384743 No abstract available.
84 results