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Strategy for genotoxicity testing and stratification of genotoxicity test results--report on initial activities of the IWGT Expert Group.
Müller L, Blakey D, Dearfield KL, Galloway S, Guzzie P, Hayashi M, Kasper P, Kirkland D, MacGregor JT, Parry JM, Schechtman L, Smith A, Tanaka N, Tweats D, Yamasaki H; IWGT Expert Group. Müller L, et al. Among authors: hayashi m. Mutat Res. 2003 Oct 7;540(2):177-81. doi: 10.1016/j.mrgentox.2003.07.007. Mutat Res. 2003. PMID: 14550501 No abstract available.
Reduction of use of animals in regulatory genotoxicity testing: Identification and implementation opportunities-Report from an ECVAM workshop.
Pfuhler S, Kirkland D, Kasper P, Hayashi M, Vanparys P, Carmichael P, Dertinger S, Eastmond D, Elhajouji A, Krul C, Rothfuss A, Schoening G, Smith A, Speit G, Thomas C, van Benthem J, Corvi R. Pfuhler S, et al. Among authors: hayashi m. Mutat Res. 2009 Nov-Dec;680(1-2):31-42. doi: 10.1016/j.mrgentox.2009.09.002. Epub 2009 Sep 16. Mutat Res. 2009. PMID: 19765670
Strategies in case of positive in vivo results in genotoxicity testing.
Thybaud V, Macgregor JT, Müller L, Crebelli R, Dearfield K, Douglas G, Farmer PB, Gocke E, Hayashi M, Lovell DP, Lutz WK, Marzin D, Moore M, Nohmi T, Phillips DH, Van Benthem J. Thybaud V, et al. Among authors: hayashi m. Mutat Res. 2011 Aug 16;723(2):121-8. doi: 10.1016/j.mrgentox.2010.09.002. Epub 2010 Sep 17. Mutat Res. 2011. PMID: 20854927
Summary of major conclusions from the 6th International Workshop on Genotoxicity Testing (IWGT), Foz do Iguaçu, Brazil.
Martus HJ, Hayashi M, Honma M, Kasper P, Gollapudi B, Mueller L, Schoeny R, Uno Y, Kirkland DJ. Martus HJ, et al. Among authors: hayashi m. Mutat Res Genet Toxicol Environ Mutagen. 2015 May 1;783:1-5. doi: 10.1016/j.mrgentox.2015.02.004. Epub 2015 Feb 26. Mutat Res Genet Toxicol Environ Mutagen. 2015. PMID: 25953394 No abstract available.
IWGT report on quantitative approaches to genotoxicity risk assessment I. Methods and metrics for defining exposure-response relationships and points of departure (PoDs).
MacGregor JT, Frötschl R, White PA, Crump KS, Eastmond DA, Fukushima S, Guérard M, Hayashi M, Soeteman-Hernández LG, Kasamatsu T, Levy DD, Morita T, Müller L, Schoeny R, Schuler MJ, Thybaud V, Johnson GE. MacGregor JT, et al. Among authors: hayashi m. Mutat Res Genet Toxicol Environ Mutagen. 2015 May 1;783:55-65. doi: 10.1016/j.mrgentox.2014.09.011. Epub 2014 Oct 13. Mutat Res Genet Toxicol Environ Mutagen. 2015. PMID: 25953400 Free article.
IWGT report on quantitative approaches to genotoxicity risk assessment II. Use of point-of-departure (PoD) metrics in defining acceptable exposure limits and assessing human risk.
MacGregor JT, Frötschl R, White PA, Crump KS, Eastmond DA, Fukushima S, Guérard M, Hayashi M, Soeteman-Hernández LG, Johnson GE, Kasamatsu T, Levy DD, Morita T, Müller L, Schoeny R, Schuler MJ, Thybaud V. MacGregor JT, et al. Among authors: hayashi m. Mutat Res Genet Toxicol Environ Mutagen. 2015 May 1;783:66-78. doi: 10.1016/j.mrgentox.2014.10.008. Epub 2014 Oct 27. Mutat Res Genet Toxicol Environ Mutagen. 2015. PMID: 25953401 Free article.
How to reduce false positive results when undertaking in vitro genotoxicity testing and thus avoid unnecessary follow-up animal tests: Report of an ECVAM Workshop.
Kirkland D, Pfuhler S, Tweats D, Aardema M, Corvi R, Darroudi F, Elhajouji A, Glatt H, Hastwell P, Hayashi M, Kasper P, Kirchner S, Lynch A, Marzin D, Maurici D, Meunier JR, Müller L, Nohynek G, Parry J, Parry E, Thybaud V, Tice R, van Benthem J, Vanparys P, White P. Kirkland D, et al. Among authors: hayashi m. Mutat Res. 2007 Mar 30;628(1):31-55. doi: 10.1016/j.mrgentox.2006.11.008. Epub 2007 Jan 13. Mutat Res. 2007. PMID: 17293159
In vivo erythrocyte micronucleus assay III. Validation and regulatory acceptance of automated scoring and the use of rat peripheral blood reticulocytes, with discussion of non-hematopoietic target cells and a single dose-level limit test.
Hayashi M, MacGregor JT, Gatehouse DG, Blakey DH, Dertinger SD, Abramsson-Zetterberg L, Krishna G, Morita T, Russo A, Asano N, Suzuki H, Ohyama W, Gibson D; In Vivo Micronucleus Assay Working Group, IWGT. Hayashi M, et al. Mutat Res. 2007 Feb 3;627(1):10-30. doi: 10.1016/j.mrgentox.2006.08.010. Epub 2006 Dec 6. Mutat Res. 2007. PMID: 17157053
7,125 results