Darville MI - Search Results

1

Discovery of gene networks regulating cytokine-induced dysfunction and apoptosis in insulin-producing INS-1 cells.

Kutlu B, Cardozo AK, Darville MI, Kruhøffer M, Magnusson N, Ørntoft T, Eizirik DL. Kutlu B, et al. Among authors: darville mi. Diabetes. 2003 Nov;52(11):2701-19. doi: 10.2337/diabetes.52.11.2701. Diabetes. 2003. PMID: 14578289

2

Use of microarray analysis to unveil transcription factor and gene networks contributing to Beta cell dysfunction and apoptosis.

Eizirik DL, Kutlu B, Rasschaert J, Darville M, Cardozo AK. Eizirik DL, et al. Ann N Y Acad Sci. 2003 Nov;1005:55-74. doi: 10.1196/annals.1288.007. Ann N Y Acad Sci. 2003. PMID: 14679040

3

Double-stranded RNA cooperates with interferon-gamma and IL-1 beta to induce both chemokine expression and nuclear factor-kappa B-dependent apoptosis in pancreatic beta-cells: potential mechanisms for viral-induced insulitis and beta-cell death in type 1 diabetes mellitus.

Liu D, Cardozo AK, Darville MI, Eizirik DL. Liu D, et al. Among authors: darville mi. Endocrinology. 2002 Apr;143(4):1225-34. doi: 10.1210/endo.143.4.8737. Endocrinology. 2002. PMID: 11897677

4

Molecular regulation of monocyte chemoattractant protein-1 expression in pancreatic beta-cells.

Kutlu B, Darville MI, Cardozo AK, Eizirik DL. Kutlu B, et al. Among authors: darville mi. Diabetes. 2003 Feb;52(2):348-55. doi: 10.2337/diabetes.52.2.348. Diabetes. 2003. PMID: 12540607

5

An octamer motif is required for activation of the inducible nitric oxide synthase promoter in pancreatic beta-cells.

Darville MI, Terryn S, Eizirik DL. Darville MI, et al. Endocrinology. 2004 Mar;145(3):1130-6. doi: 10.1210/en.2003-1200. Epub 2003 Nov 20. Endocrinology. 2004. PMID: 14630716

6

Notch signaling: a mediator of beta-cell de-differentiation in diabetes?

Darville MI, Eizirik DL. Darville MI, et al. Biochem Biophys Res Commun. 2006 Jan 27;339(4):1063-8. doi: 10.1016/j.bbrc.2005.11.111. Epub 2005 Dec 1. Biochem Biophys Res Commun. 2006. PMID: 16337608

7

Double-stranded ribonucleic acid (RNA) induces beta-cell Fas messenger RNA expression and increases cytokine-induced beta-cell apoptosis.

Liu D, Darville M, Eizirik DL. Liu D, et al. Endocrinology. 2001 Jun;142(6):2593-9. doi: 10.1210/endo.142.6.8188. Endocrinology. 2001. PMID: 11356709

8

Inhibition of cytokine-induced NF-kappaB activation by adenovirus-mediated expression of a NF-kappaB super-repressor prevents beta-cell apoptosis.

Heimberg H, Heremans Y, Jobin C, Leemans R, Cardozo AK, Darville M, Eizirik DL. Heimberg H, et al. Diabetes. 2001 Oct;50(10):2219-24. doi: 10.2337/diabetes.50.10.2219. Diabetes. 2001. PMID: 11574401

9

Regulation by cytokines of the inducible nitric oxide synthase promoter in insulin-producing cells.

Darville MI, Eizirik DL. Darville MI, et al. Diabetologia. 1998 Sep;41(9):1101-8. doi: 10.1007/s001250051036. Diabetologia. 1998. PMID: 9754830

10

NF-kappaB is required for cytokine-induced manganese superoxide dismutase expression in insulin-producing cells.

Darville MI, Ho YS, Eizirik DL. Darville MI, et al. Endocrinology. 2000 Jan;141(1):153-62. doi: 10.1210/endo.141.1.7268. Endocrinology. 2000. PMID: 10614634

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