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416 results

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Benzyl vinylogous amide substituted aryldihydropyridazinones and aryldimethylpyrazolones as potent and selective PDE3B inhibitors.
Edmondson SD, Mastracchio A, He J, Chung CC, Forrest MJ, Hofsess S, MacIntyre E, Metzger J, O'Connor N, Patel K, Tong X, Tota MR, Van der Ploeg LH, Varnerin JP, Fisher MH, Wyvratt MJ, Weber AE, Parmee ER. Edmondson SD, et al. Among authors: macintyre e. Bioorg Med Chem Lett. 2003 Nov 17;13(22):3983-7. doi: 10.1016/j.bmcl.2003.08.056. Bioorg Med Chem Lett. 2003. PMID: 14592490
Synthesis and SAR of potent and orally bioavailable tert-butylpyrrolidine archetype derived melanocortin subtype-4 receptor modulators.
Guo L, Ye Z, Ujjainwalla F, Sings HL, Sebhat IK, Huber J, Weinberg DH, Tang R, MacNeil T, Tamvakopoulos C, Peng Q, MacIntyre E, van der Ploeg LH, Goulet MT, Wyvratt MJ, Nargund RP. Guo L, et al. Among authors: macintyre e. Bioorg Med Chem Lett. 2008 Jun 1;18(11):3242-7. doi: 10.1016/j.bmcl.2008.04.049. Epub 2008 Apr 25. Bioorg Med Chem Lett. 2008. PMID: 18479920
L-750355, a human beta3-adrenoceptor agonist; in vitro pharmacology and profile of activity in vivo in the rhesus monkey.
Forrest MJ, Hom G, Bach T, Candelore MR, Cascieri MA, Strader C, Tota L, Fisher MH, Szumiloski J, Ok HO, Weber AE, Wyvratt M, Vicario P, Marko O, Deng L, Cioffe C, Hegarty-Friscino B, MacIntyre E. Forrest MJ, et al. Among authors: macintyre e. Eur J Pharmacol. 2000 Oct 27;407(1-2):175-81. doi: 10.1016/s0014-2999(00)00724-x. Eur J Pharmacol. 2000. PMID: 11050305
The role of melanocortins in body weight regulation: opportunities for the treatment of obesity.
MacNeil DJ, Howard AD, Guan X, Fong TM, Nargund RP, Bednarek MA, Goulet MT, Weinberg DH, Strack AM, Marsh DJ, Chen HY, Shen CP, Chen AS, Rosenblum CI, MacNeil T, Tota M, MacIntyre ED, Van der Ploeg LH. MacNeil DJ, et al. Eur J Pharmacol. 2002 Apr 12;440(2-3):141-57. doi: 10.1016/s0014-2999(02)01425-5. Eur J Pharmacol. 2002. Corrected and republished in: Eur J Pharmacol. 2002 Aug 16;450(1):93-109. doi: 10.1016/s0014-2999(02)01989-1 PMID: 12007532 Corrected and republished. Review.
A novel 3-dimensional micro-ultrasound approach to automated measurement of carotid arterial plaque volume as a biomarker for experimental atherosclerosis.
Walker M 3rd, Campbell BR, Azer K, Tong C, Fang K, Cook JJ, Forrest MJ, Kempadoo K, Wright SD, Saltzman JS, MacIntyre E, Hargreaves R. Walker M 3rd, et al. Among authors: macintyre e. Atherosclerosis. 2009 May;204(1):55-65. doi: 10.1016/j.atherosclerosis.2008.09.013. Epub 2008 Sep 19. Atherosclerosis. 2009. PMID: 19135672
Midodrine for the early liberation from vasopressor support in the ICU (LIBERATE): a feasibility study.
Kilcommons SJ, Hammal F, Opgenorth DL, Fiest KM, Karvellas CJ, Lau VI, MacIntyre E, Senaratne J, Slemko J, Sligl W, Zampieri F, Duquette D', Guan LT, Baig N, Bagshaw SM, Rewa OG. Kilcommons SJ, et al. Among authors: macintyre e. Pilot Feasibility Stud. 2024 Dec 4;10(1):147. doi: 10.1186/s40814-024-01577-2. Pilot Feasibility Stud. 2024. PMID: 39633467 Free PMC article.
Adjunctive Midodrine Therapy for Vasopressor-Dependent Shock in the ICU: A Systematic Review and Meta-Analysis.
Kilcommons SJ, Hammal F, Kamaleldin M, Opgenorth DL, Fiest KM, Karvellas CJ, Kutsogiannis DJ, Lau VI, MacIntyre EJ, Rochwerg B, Senaratne JM, Slemko JM, Sligl WI, Wang XXM, Bagshaw SM, Rewa OG. Kilcommons SJ, et al. Among authors: macintyre ej. Crit Care Med. 2024 Dec 4. doi: 10.1097/CCM.0000000000006519. Online ahead of print. Crit Care Med. 2024. PMID: 39631091
416 results