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mTOR-dependent regulation of ribosomal gene transcription requires S6K1 and is mediated by phosphorylation of the carboxy-terminal activation domain of the nucleolar transcription factor UBF.
Hannan KM, Brandenburger Y, Jenkins A, Sharkey K, Cavanaugh A, Rothblum L, Moss T, Poortinga G, McArthur GA, Pearson RB, Hannan RD. Hannan KM, et al. Among authors: cavanaugh a. Mol Cell Biol. 2003 Dec;23(23):8862-77. doi: 10.1128/MCB.23.23.8862-8877.2003. Mol Cell Biol. 2003. PMID: 14612424 Free PMC article.
Rrn3 becomes inactivated in the process of ribosomal DNA transcription.
Hirschler-Laszkiewicz I, Cavanaugh AH, Mirza A, Lun M, Hu Q, Smink T, Rothblum LI. Hirschler-Laszkiewicz I, et al. Among authors: cavanaugh ah. J Biol Chem. 2003 May 23;278(21):18953-9. doi: 10.1074/jbc.M301093200. Epub 2003 Mar 19. J Biol Chem. 2003. PMID: 12646563 Free article.
The role of acetylation in rDNA transcription.
Hirschler-Laszkiewicz I, Cavanaugh A, Hu Q, Catania J, Avantaggiati ML, Rothblum LI. Hirschler-Laszkiewicz I, et al. Among authors: cavanaugh a. Nucleic Acids Res. 2001 Oct 15;29(20):4114-24. doi: 10.1093/nar/29.20.4114. Nucleic Acids Res. 2001. PMID: 11600700 Free PMC article.
106 results