Okar DA - Search Results

1

A potential role for fructose-2,6-bisphosphate in the stimulation of hepatic glucokinase gene expression.

Wu C, Okar DA, Stoeckman AK, Peng LJ, Herrera AH, Herrera JE, Towle HC, Lange AJ. Wu C, et al. Among authors: okar da. Endocrinology. 2004 Feb;145(2):650-8. doi: 10.1210/en.2003-1290. Epub 2003 Nov 14. Endocrinology. 2004. PMID: 14617577

2

Increasing fructose 2,6-bisphosphate overcomes hepatic insulin resistance of type 2 diabetes.

Wu C, Okar DA, Newgard CB, Lange AJ. Wu C, et al. Among authors: okar da. Am J Physiol Endocrinol Metab. 2002 Jan;282(1):E38-45. doi: 10.1152/ajpendo.2002.282.1.E38. Am J Physiol Endocrinol Metab. 2002. PMID: 11739081 Free article.

3

Elucidation of the role of fructose 2,6-bisphosphate in the regulation of glucose fluxes in mice using in vivo (13)C NMR measurements of hepatic carbohydrate metabolism.

Choi IY, Wu C, Okar DA, Lange AJ, Gruetter R. Choi IY, et al. Among authors: okar da. Eur J Biochem. 2002 Sep;269(18):4418-26. Eur J Biochem. 2002. PMID: 12230553 Free article.

4

Reduction of hepatic glucose production as a therapeutic target in the treatment of diabetes.

Wu C, Okar DA, Kang J, Lange AJ. Wu C, et al. Among authors: okar da. Curr Drug Targets Immune Endocr Metabol Disord. 2005 Mar;5(1):51-9. doi: 10.2174/1568008053174769. Curr Drug Targets Immune Endocr Metabol Disord. 2005. PMID: 15777204 Review.

5

Enhancing hepatic glycolysis reduces obesity: differential effects on lipogenesis depend on site of glycolytic modulation.

Wu C, Kang JE, Peng LJ, Li H, Khan SA, Hillard CJ, Okar DA, Lange AJ. Wu C, et al. Among authors: okar da. Cell Metab. 2005 Aug;2(2):131-40. doi: 10.1016/j.cmet.2005.07.003. Cell Metab. 2005. PMID: 16098830 Free article.

6

Molecular coordination of hepatic glucose metabolism by the 6-phosphofructo-2-kinase/fructose-2,6- bisphosphatase:glucokinase complex.

Smith WE, Langer S, Wu C, Baltrusch S, Okar DA. Smith WE, et al. Among authors: okar da. Mol Endocrinol. 2007 Jun;21(6):1478-87. doi: 10.1210/me.2006-0356. Epub 2007 Mar 20. Mol Endocrinol. 2007. PMID: 17374851

7

Fructose-2,6-bisphosphate and control of carbohydrate metabolism in eukaryotes.

Okar DA, Lange AJ. Okar DA, et al. Biofactors. 1999;10(1):1-14. doi: 10.1002/biof.5520100101. Biofactors. 1999. PMID: 10475585 Review.

8

Overexpression of 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase in mouse liver lowers blood glucose by suppressing hepatic glucose production.

Wu C, Okar DA, Newgard CB, Lange AJ. Wu C, et al. Among authors: okar da. J Clin Invest. 2001 Jan;107(1):91-8. doi: 10.1172/JCI11103. J Clin Invest. 2001. PMID: 11134184 Free PMC article.

9

Interaction of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (PFK-2/FBPase-2) with glucokinase activates glucose phosphorylation and glucose metabolism in insulin-producing cells.

Massa L, Baltrusch S, Okar DA, Lange AJ, Lenzen S, Tiedge M. Massa L, et al. Among authors: okar da. Diabetes. 2004 Apr;53(4):1020-9. doi: 10.2337/diabetes.53.4.1020. Diabetes. 2004. PMID: 15047617

10

Regulation of the regulatory enzyme, 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase.

Okar DA, Wu C, Lange AJ. Okar DA, et al. Adv Enzyme Regul. 2004;44:123-54. doi: 10.1016/j.advenzreg.2003.11.006. Adv Enzyme Regul. 2004. PMID: 15581487 Review. No abstract available.

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