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Variously substituted (phosphonoacetamido)oxy analogues of geranylgeranyl diphosphate (GGdP) as GGdP-transferase (GGTase) inhibitors and antiproliferative agents.
Minutolo F, Asso V, Bertini S, Betti L, Ciriaco M, Danesi R, Gervasi G, Ghilardi E, Giovanetti E, Giannaccini G, Placanica G, Prota G, Rapposelli S, Macchia M. Minutolo F, et al. Among authors: placanica g. Med Chem. 2005 May;1(3):239-44. doi: 10.2174/1573406053765512. Med Chem. 2005. PMID: 16787319
Synthesis of stable analogues of geranylgeranyl diphosphate possessing a (Z,E,E)-geranylgeranyl side chain, docking analysis, and biological assays for prenyl protein transferase inhibition.
Minutolo F, Bertini S, Betti L, Danesi R, Gervasi G, Giannaccini G, Martinelli A, Papini AM, Peroni E, Placanica G, Rapposelli S, Tuccinardi T, Macchia M. Minutolo F, et al. Among authors: placanica g. ChemMedChem. 2006 Feb;1(2):218-24. doi: 10.1002/cmdc.200500010. ChemMedChem. 2006. PMID: 16892354
28 results