Mayr LM - Search Results

1

SpeedScreen: label-free liquid chromatography-mass spectrometry-based high-throughput screening for the discovery of orphan protein ligands.

Muckenschnabel I, Falchetto R, Mayr LM, Filipuzzi I. Muckenschnabel I, et al. Among authors: mayr lm. Anal Biochem. 2004 Jan 15;324(2):241-9. doi: 10.1016/j.ab.2003.09.040. Anal Biochem. 2004. PMID: 14690688

2

SpeedScreen: The "missing link" between genomics and lead discovery.

Zehender H, Le Goff F, Lehmann N, Filipuzzi I, Mayr LM. Zehender H, et al. Among authors: mayr lm. J Biomol Screen. 2004 Sep;9(6):498-505. doi: 10.1177/1087057104267605. J Biomol Screen. 2004. PMID: 15452336

3

Synthesis and characterization of fluorescent ubiquitin derivatives as highly sensitive substrates for the deubiquitinating enzymes UCH-L3 and USP-2.

Tirat A, Schilb A, Riou V, Leder L, Gerhartz B, Zimmermann J, Worpenberg S, Eidhoff U, Freuler F, Stettler T, Mayr L, Ottl J, Leuenberger B, Filipuzzi I. Tirat A, et al. Anal Biochem. 2005 Aug 15;343(2):244-55. doi: 10.1016/j.ab.2005.04.023. Anal Biochem. 2005. PMID: 15963938

4

Development and implementation of a highly miniaturized confocal 2D-FIDA-based high-throughput screening assay to search for active site modulators of the human heat shock protein 90beta.

Schilb A, Riou V, Schoepfer J, Ottl J, Müller K, Chene P, Mayr LM, Filipuzzi I. Schilb A, et al. Among authors: mayr lm. J Biomol Screen. 2004 Oct;9(7):569-77. doi: 10.1177/1087057104265538. J Biomol Screen. 2004. PMID: 15475476

5

A chemoinformatics analysis of hit lists obtained from high-throughput affinity-selection screening.

Brown N, Zehender H, Azzaoui K, Schuffenhauer A, Mayr LM, Jacoby E. Brown N, et al. Among authors: mayr lm. J Biomol Screen. 2006 Mar;11(2):123-30. doi: 10.1177/1087057105283579. Epub 2005 Dec 16. J Biomol Screen. 2006. PMID: 16361695

6

Application of mass spectrometry technologies for the discovery of low-molecular weight modulators of enzymes and protein-protein interactions.

Zehender H, Mayr LM. Zehender H, et al. Among authors: mayr lm. Curr Opin Chem Biol. 2007 Oct;11(5):511-7. doi: 10.1016/j.cbpa.2007.08.031. Epub 2007 Oct 10. Curr Opin Chem Biol. 2007. PMID: 17931957 Review.

7

Knowledge-based virtual screening: application to the MDM4/p53 protein-protein interaction.

Jacoby E, Boettcher A, Mayr LM, Brown N, Jenkins JL, Kallen J, Engeloch C, Schopfer U, Furet P, Masuya K, Lisztwan J. Jacoby E, et al. Among authors: mayr lm. Methods Mol Biol. 2009;575:173-94. doi: 10.1007/978-1-60761-274-2_7. Methods Mol Biol. 2009. PMID: 19727615

8

Readout technologies for highly miniaturized kinase assays applicable to high-throughput screening in a 1536-well format.

Klumpp M, Boettcher A, Becker D, Meder G, Blank J, Leder L, Forstner M, Ottl J, Mayr LM. Klumpp M, et al. Among authors: mayr lm. J Biomol Screen. 2006 Sep;11(6):617-33. doi: 10.1177/1087057106288444. Epub 2006 Jun 7. J Biomol Screen. 2006. PMID: 16760365

9

Optimization of protein expression systems for modern drug discovery.

Forstner M, Leder L, Mayr LM. Forstner M, et al. Among authors: mayr lm. Expert Rev Proteomics. 2007 Feb;4(1):67-78. doi: 10.1586/14789450.4.1.67. Expert Rev Proteomics. 2007. PMID: 17288516 Review.

10

Fragment-based screening by biochemical assays: Systematic feasibility studies with trypsin and MMP12.

Boettcher A, Ruedisser S, Erbel P, Vinzenz D, Schiering N, Hassiepen U, Rigollier P, Mayr LM, Woelcke J. Boettcher A, et al. Among authors: mayr lm. J Biomol Screen. 2010 Oct;15(9):1029-41. doi: 10.1177/1087057110380455. Epub 2010 Sep 20. J Biomol Screen. 2010. PMID: 20855559

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