Manolagas SC - Search Results

1

Glucocorticoids act directly on osteoblasts and osteocytes to induce their apoptosis and reduce bone formation and strength.

O'Brien CA, Jia D, Plotkin LI, Bellido T, Powers CC, Stewart SA, Manolagas SC, Weinstein RS. O'Brien CA, et al. Among authors: manolagas sc. Endocrinology. 2004 Apr;145(4):1835-41. doi: 10.1210/en.2003-0990. Epub 2003 Dec 22. Endocrinology. 2004. PMID: 14691012

2

Transduction of cell survival signals by connexin-43 hemichannels.

Plotkin LI, Manolagas SC, Bellido T. Plotkin LI, et al. Among authors: manolagas sc. J Biol Chem. 2002 Mar 8;277(10):8648-57. doi: 10.1074/jbc.M108625200. Epub 2001 Dec 10. J Biol Chem. 2002. PMID: 11741942 Free article.

3

Promotion of osteoclast survival and antagonism of bisphosphonate-induced osteoclast apoptosis by glucocorticoids.

Weinstein RS, Chen JR, Powers CC, Stewart SA, Landes RD, Bellido T, Jilka RL, Parfitt AM, Manolagas SC. Weinstein RS, et al. Among authors: manolagas sc. J Clin Invest. 2002 Apr;109(8):1041-8. doi: 10.1172/JCI14538. J Clin Invest. 2002. PMID: 11956241 Free PMC article.

4

Divergent effects of selective peroxisome proliferator-activated receptor-gamma 2 ligands on adipocyte versus osteoblast differentiation.

Lecka-Czernik B, Moerman EJ, Grant DF, Lehmann JM, Manolagas SC, Jilka RL. Lecka-Czernik B, et al. Among authors: manolagas sc. Endocrinology. 2002 Jun;143(6):2376-84. doi: 10.1210/endo.143.6.8834. Endocrinology. 2002. PMID: 12021203

5

Parathyroid hormone stimulates receptor activator of NFkappa B ligand and inhibits osteoprotegerin expression via protein kinase A activation of cAMP-response element-binding protein.

Fu Q, Jilka RL, Manolagas SC, O'Brien CA. Fu Q, et al. Among authors: manolagas sc. J Biol Chem. 2002 Dec 13;277(50):48868-75. doi: 10.1074/jbc.M208494200. Epub 2002 Oct 2. J Biol Chem. 2002. PMID: 12364326 Free article.

6

Kinase-mediated regulation of common transcription factors accounts for the bone-protective effects of sex steroids.

Kousteni S, Han L, Chen JR, Almeida M, Plotkin LI, Bellido T, Manolagas SC. Kousteni S, et al. Among authors: manolagas sc. J Clin Invest. 2003 Jun;111(11):1651-64. doi: 10.1172/JCI17261. J Clin Invest. 2003. PMID: 12782668 Free PMC article.

7

Proteasomal degradation of Runx2 shortens parathyroid hormone-induced anti-apoptotic signaling in osteoblasts. A putative explanation for why intermittent administration is needed for bone anabolism.

Bellido T, Ali AA, Plotkin LI, Fu Q, Gubrij I, Roberson PK, Weinstein RS, O'Brien CA, Manolagas SC, Jilka RL. Bellido T, et al. Among authors: manolagas sc. J Biol Chem. 2003 Dec 12;278(50):50259-72. doi: 10.1074/jbc.M307444200. Epub 2003 Oct 1. J Biol Chem. 2003. PMID: 14523023 Free article.

8

The skeletal effects of glucocorticoid excess override those of orchidectomy in mice.

Weinstein RS, Jia D, Powers CC, Stewart SA, Jilka RL, Parfitt AM, Manolagas SC. Weinstein RS, et al. Among authors: manolagas sc. Endocrinology. 2004 Apr;145(4):1980-7. doi: 10.1210/en.2003-1133. Epub 2004 Jan 8. Endocrinology. 2004. PMID: 14715712

9

In vivo visualization of aging-associated gene transcription: evidence for free radical theory of aging.

Zhang J, Dai J, Lu Y, Yao Z, O'Brien CA, Murtha JM, Qi W, Hall DE, Manolagas SC, Ershler WB, Keller ET. Zhang J, et al. Among authors: manolagas sc. Exp Gerontol. 2004 Feb;39(2):239-47. doi: 10.1016/j.exger.2003.10.024. Exp Gerontol. 2004. PMID: 15036418

10

Kinase-mediated transcription, activators of nongenotropic estrogen-like signaling (ANGELS), and osteoporosis: a different perspective on the HRT dilemma.

Manolagas SC, Kousteni S, Chen JR, Schuller M, Plotkin L, Bellido T. Manolagas SC, et al. Kidney Int Suppl. 2004 Oct;(91):S41-9. doi: 10.1111/j.1523-1755.2004.09107.x. Kidney Int Suppl. 2004. PMID: 15461702 Free article. Review.

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